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Nanobodies

A Proline-Rich-Domain-Binding Single Domain Antibody Selectively Inhibits RNA-Induced Phase Separation of Tau

Simon Thiou, Leslie Martin, Evangelia Manousaki, Marine Nguyen, Justine Mortelecque, Leila Heidsieck, François-Xavier Cantrelle, David Blum, Valérie Buée-Scherrer, Luc Buée, Isabelle Landrieu, Elian Dupré, and Clément Danis

(2026) ACS Chemical Neuroscience Article ASAP DOI: 10.1021/acschemneuro.6c00110

Development

A Caenorhabditis elegans spatiotemporal proximity atlas reveals the MAPK p38 as a generator of phenotypic plasticity in vivo

Wang Yuan, Luke A. Nunamaker, Yi M. Weaver, and Benjamin P. Weaver

(2026) Science Signaling 5 May 2026 Vol 19, Issue 936 DOI: 10.1126/scisignal.aeb4530

Nanobodies

Selective Nanobody-Derived Minibodies Targeting Galectin-1 and -7 Reveal Non-Redundant Glyco-Immune Functions and Therapeutic Potential in Triple-Negative Breast Cancer

Rita Nehmé,Marlène Fortier,Philippine Granger, Joly de Boissel,France Caza,Fanny Fronton,Léa Bourguignon,Tania Charpentier,Camille Fuselier,Sophia Ferchiou,Noémie D’Auteuil,Louis Gaboury,Alain Lamarre,David Chatenet,Yves St-Pierre

(2026) Journal of Medicinal Chemistry, American Chemical Society SN - 0022-2623 M3 - doi: 10.1021/acs.jmedchem.6c00142

Plant Biology

Attenuation of cell-cell movement of tobamoviruses by the C-terminal GPI signal peptide of arabinogalactan protein FLA8

Yumin Kan, Phu-Tri Tran, Benoıˆt Lacroix, Vitaly Citovsky

(2026) Current Biology 36, 1–10 May 4, https://doi.org/10.1016/j.cub.2026.03.065

Cell Biology - Development

Drak is a potential binding partner of Drosophila Filamin

Riku O. Korkiamäki, Chandan Thapa, Hannah J. Green, Jari Ylänne

(2026) Biology Open bio.062185. https://doi.org/10.1242/bio.062185

Microbiology

A cluster of acidic residues in the cytoplasmic domain of SARS-CoV-2 Spike is required for virion-incorporation and infectivity

Charlotte A. Stoneham, Rajendra Singh, Amalia De Leon, Petra Tafelmeyer, Francisco Acosta, Angus Fuori, Michael Anderson, Peter W. Ramirez, Hannah S. Schwartzer-Sperber, Satish Pillai, Mary K. Lewinski, John Guatelli

(2026) Plos One, March 12 https://doi.org/10.1371/journal.pone.0340644

Microbiology

Anaplasma phagocytophilum invasin AipB interacts with the β2 integrin β-subunit CD18 to orchestrate infection

Mary Clark H. Lind, Waheeda A. Naimi, Jason R. Hunt, Jerilyn R. Izac, Richard T. Marconi, Jason A. Carlyon

(2026) Host - Microbial Interactions, mBio 0:e03853-25. https://doi.org/10.1128/mbio.03853-25

Plant Biology - Cell Biology

A lineage-specific selective autophagy receptor module mediates P-body turnover

Alibek Abdrakhmanov, Elizabeth Ethier, Aleksandra S. Anisimova, Nenad Grujic, Ranjith K. Papareddy, Marion Clavel, G. Elif Karagöz, Erinc Hallacli, Yasin Dagdas

(2026) Developmental Cell, ISSN 1534-5807, https://doi.org/10.1016/j.devcel.2026.01.017.

Cell Biology - Immunology

First Glance at Myeloid Leukaemia Factor 2 in Cardiomyocytes

Jakob Christoph Voran, Lucia Sophie Kilian, Simone Martini, Marcin Luzarowski, Marie Isabel Noormalal, Oliver Josef Müller,Ashraf Yusuf Rangrez and Derk Frank

(2025) J. Cardiovasc. Dev. Dis., 13(1), 19; https://doi.org/10.3390/jcdd13010019

Nanobodies

Selection and Optimization Strategy for Rap1-Targeting Single Domain Antibodies as Platelet Activation markers

Marie-Christine Alessi, Maxime Moulard, Daniele Boulay-Moine, Cyril Pons, Marielle Margier, Cléa Vessière, Marjorie Poggi, Theo Pigaglio, Francoise Dignat George, Alain Roussel, Stéphane Burtey, Laurent Bonello, Patrick Chames, Remi Bonjean, Franck Peiretti

(2025) Research and Practice in Thrombosis and Haemostasis, DOI: https://doi.org/10.1016/j.rpth.2025.103294

Plant Biology

Arabidopsis Microtubule-BRI1 Associated Proteins negatively regulate hypocotyl elongation by controlling brassinosteroid-dependent cortical microtubule reorientation

Charlotte Delesalle, Alvaro Montiel-Jorda, Rakuri Aiba, Julien Spielmann, Julie Neveu, Satoshi Fujita, Grégory Vert

(2025) Plant Communications, DOI: https://doi.org/10.1016/j.xplc.2025.101637

Molecular Biology

A General Synthesis Approach to Double-Guanidinium Stapled Peptides and Foldamers

Maxime Neuville, Marta Martin Bornez, Mathieu Bourgeais, Hugues Samueli, Laura Mauran, Sébastien R. Goudreau, Abdel-Majid Khatib, Gilles Guichard, and Morgane Pasco

(2025) ChemEurJ Research Article doi.org/10.1002/chem.202502273