Hybrigenics publications
597 result(s)
Please find below a selection of published articles reporting the biochemical and functional validation of protein interactions discovered using Hybrigenics Yeast Two-Hybrid technology, ULTImate Y2HTM, or other services.
Neuroscience - Molecular Biology
Secretion of VGF relies on the interplay between LRRK2 and post-Golgi v-SNAREs
https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00232-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124723002322%3Fshowall%3DtrueMetabolism - Molecular Biology
NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes
https://www.cell.com/iscience/pdf/S2589-0042(23)00390-5.pdf?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004223003905%3Fshowall%3DtruePlant Biology - Molecular Biology
FKF1 Interacts with CHUP1 and Regulates Chloroplast Movement in Arabidopsis
https://www.mdpi.com/2223-7747/12/3/542Cell Biology - Molecular Biology
The Nuclear Transporter Importin 13 Can Regulate Stress-Induced Cell Death through the Clusterin/KU70 Axis
https://www.mdpi.com/2073-4409/12/2/279Molecular Biology
The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
https://doi.org/10.1016/j.celrep.2022.111902Cell Biology - Microbiology
A bacterial virulence factor interacts with the splicing factor RBM5 and stimulates formation of nuclear RBM5 granules
https://www.nature.com/articles/s41598-022-26037-wPlant Biology
Phytocyanin-encoding genes confer enhanced ozone tolerance in Arabidopsis thaliana
https://www.nature.com/articles/s41598-022-25706-0#Sec1Nanobodies
DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody
https://pubs.acs.org/doi/full/10.1021/jacs.2c10656Cell Biology - Microbiology
IMC10 and LMF1 mediate mitochondrial morphology through mitochondrion–pellicle contact sites in Toxoplasma gondii
https://journals.biologists.com/jcs/article/135/22/jcs260083/282114/IMC10-and-LMF1-mediate-mitochondrial-morphologyMicrobiology - Plant Biology
The Arabidopsis E3 ubiquitin ligase PUB4 regulates BIK1 and is targeted by a bacterial type-III effector
https://www.embopress.org/doi/abs/10.15252/embj.2020107257Development - Plant Biology
The DC1 domain protein BINUCLEATE POLLEN is required for pollen development in Arabidopsis thaliana
https://pubmed.ncbi.nlm.nih.gov/36001044/Plant Biology
Topoisomerase VI participates in an insulator-like function that prevents H3K9me2 spreading
https://www.pnas.org/doi/abs/10.1073/pnas.2001290119Cell Biology
Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis
https://www.sciencedirect.com/science/article/abs/pii/S0092867422004585Cell Biology - Metabolism
Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1
https://pubmed.ncbi.nlm.nih.gov/35752171/Cell Biology
Interactions between C8orf37 and FAM161A, Two Ciliary Proteins Essential for Photoreceptor Survival
https://pubmed.ncbi.nlm.nih.gov/36233334/Cancer Research - Cell Biology
A regulatory network comprising let-7 miRNA and SMUG1 is associated with good prognosis in ER+ breast tumours
https://academic.oup.com/nar/article/50/18/10449/6717838Cell Biology - Development
The exocyst complex regulates C. elegans germline stem cell proliferation by controlling membrane Notch levels
https://pubmed.ncbi.nlm.nih.gov/34338279/Cell Biology - Microbiology
TFK1, a basal body transition fibre protein that is essential for cytokinesis in Trypanosoma brucei
https://pubmed.ncbi.nlm.nih.gov/35588197/Cell Biology - Virology
TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV
https://www.nature.com/articles/s41467-021-27650-5#Sec10Cell Biology - Development
Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression
https://www.nature.com/articles/s41418-021-00915-8Cell Biology - Microbiology
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
https://pubmed.ncbi.nlm.nih.gov/35568036/Development - Plant Biology
A mitochondrial ADXR-ADX-P450 electron transport chain is essential for maternal gametophytic control of embryogenesis in Arabidopsis
https://pubmed.ncbi.nlm.nih.gov/35046016/Cell Biology - Plant Biology
Convergent selection of a WD40 protein that enhances grain yield in maize and rice
https://www.science.org/doi/pdf/10.1126/science.abg7985Cell Biology - Metabolism
Function of ceramide transfer protein for biogenesis and sphingolipid composition of extracellular vesicles
https://pubmed.ncbi.nlm.nih.gov/35642450/Plant Biology
The carboxy-terminal tail of GLR3.3 is essential forwound-response electrical signaling
https://nph.onlinelibrary.wiley.com/doi/epdf/10.1111/nph.18475Cancer Research - Cell Biology
Blocking the Farnesyl Pocket of PDEδ Reduces Rheb-Dependent mTORC1 Activation and Survival of Tsc2-Null Cells
https://pubmed.ncbi.nlm.nih.gov/35814251/Cell Biology - Development
Local synthesis of the phosphatidylinositol-3,4- bisphosphate lipid drives focal adhesion turnover
https://www.cell.com/action/showPdf?pii=S1534-5807%2822%2900451-8Cell Biology - Microbiology
Interaction between the flagellar pocket collar and the hook complex via a novel microtubule-binding protein in Trypanosoma brucei
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006710Cell Biology - Development
An integrated model for Gpr124 function in Wnt7a/b signaling among vertebrates
https://www.sciencedirect.com/science/article/pii/S2211124722006775Plant Biology
The Arabidopsis SAC9 enzyme is enriched in a cortical population of early endosomes and restricts PI(4,5)P2 at the plasma membrane
https://elifesciences.org/articles/73837Nanobodies
mNG-tagged fusion proteins and nanobodies to visualize tropomyosins in yeast and mammalian cells
https://journals.biologists.com/jcs/article/135/18/jcs260288/276794Cell Biology - Development
The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters
https://elifesciences.org/articles/80067Cell Biology - Metabolism
MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression
https://pubmed.ncbi.nlm.nih.gov/35203270/Neuroscience
The Orphan GPCR Receptor, GPR88, Interacts with Nuclear Protein Partners in the Cerebral Cortex
https://pubmed.ncbi.nlm.nih.gov/34247243/Cell Biology - Immunology
The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism
https://www.jimmunol.org/content/early/2021/12/29/jimmunol.2100705Cell Biology
A heterotypic assembly mechanism regulates CHIP E3 ligase activity
https://www.embopress.org/doi/full/10.15252/embj.2021109566Cell Biology - Metabolism
MNK2 deficiency potentiates β-cell regeneration via translational regulation
https://www.nature.com/articles/s41589-022-01047-xNanobodies
Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment
https://www.sciencedirect.com/science/article/pii/S1525001622000090#:~:text=Original%20Article-,Inhibition%20of%20Tau%20seeding%20by%20targeting%20Tau%20nucleation%20core%20within,a%20single%20domain%20antibody%20fragment&text=Tau%20proteins%20aggregate%20into%20filaments,disorders%20referred%20to%20as%20tauopathies.Nanobodies
Structural Insights into the Design of Synthetic Nanobody Libraries
https://www.mdpi.com/1420-3049/27/7/2198Nanobodies
Interaction standards for biophysics: anti lysozyme nanobodies
https://link.springer.com/content/pdf/10.1007/s00249-021-01524-6.pdfCell Biology - Microbiology
TbKINX1B: a novel BILBO1 partner and an essential protein in bloodstream form Trypanosoma brucei
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8906236/Cell Biology - Development
DCHS1, Lix1L, and the Septin Cytoskeleton: Molecular and Developmental Etiology of Mitral Valve Prolapse
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874669/Cancer Research
ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer
https://pubmed.ncbi.nlm.nih.gov/34927784/Cell Biology - Plant Biology
An oomycete effector targets a plant RNA helicase involved in root development and defense
https://pubmed.ncbi.nlm.nih.gov/34913494/Cell Biology
Rabaptin5 targets autophagy to damaged endosomes and Salmonella vacuoles via FIP200 and ATG16L1
https://pubmed.ncbi.nlm.nih.gov/34704340/Cell Biology
Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization
https://pubmed.ncbi.nlm.nih.gov/34674267/Development
RASSF8-mediated transport of Echinoid via the exocyst promotes Drosophila wing elongation and epithelial ordering
https://pubmed.ncbi.nlm.nih.gov/34532737/Cell Biology
WDR37 syndrome: identification of a distinct new cluster of disease-associated variants and functional analyses of mutant proteins
https://pubmed.ncbi.nlm.nih.gov/34642815/Metabolism
STE20-Type Kinase TAOK3 Regulates Hepatic Lipid Partitioning. Mol Metab
https://pubmed.ncbi.nlm.nih.gov/34634521/Cell Biology
Calsyntenin-3 interacts with the sodium-dependent vitamin C transporter-2 to regulate vitamin C uptake
https://www.sciencedirect.com/science/article/abs/pii/S014181302102211XMicrobiology - Virology - Plant Biology
Parasitic modulation of host development by ubiquitin-independent protein degradation
https://pubmed.ncbi.nlm.nih.gov/34536345/Cell Biology
Regulation of Fibroblast Activation Protein-α Expression: Focus on Intracellular Protein Interactions
https://pubmed.ncbi.nlm.nih.gov/34523930/Cell Biology
Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7
https://www.sciencedirect.com/science/article/abs/pii/S1931312821003036Cell Biology
TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis
https://pubmed.ncbi.nlm.nih.gov/34158398/Cell Biology
PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans
https://pubmed.ncbi.nlm.nih.gov/34003111/Cancer Research
Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library, Cell Chemical Biology
https://www.sciencedirect.com/science/article/pii/S2451945621002543#mmc1Plant Biology
JASMONATE-ZIM DOMAIN proteins engage Polycomb chromatin modifiers to modulate Jasmonate signaling in Arabidopsis
https://pubmed.ncbi.nlm.nih.gov/33676023/Cancer Research
The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer
https://pubmed.ncbi.nlm.nih.gov/33772001/Immunology
Vascular endothelial ERp72 is involved in the inflammatory response in a rat model of skeletal muscle injury
https://pubmed.ncbi.nlm.nih.gov/33398381/Immunology
Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation
https://pubmed.ncbi.nlm.nih.gov/33742095/Microbiology - Virology
The Campylobacter jejuni CiaD effector co-opts the host cell protein IQGAP1 to promote cell entry
https://pubmed.ncbi.nlm.nih.gov/33637714/Cell Biology
SPEG binds with desmin and its deficiency causes defects in triad and focal adhesion proteins
https://pubmed.ncbi.nlm.nih.gov/33355670/Plant Biology
Transgenic insertion of the cyanobacterial membrane protein ictB increases grain yield in Zea mays through increased photosynthesis and carbohydrate production
https://pubmed.ncbi.nlm.nih.gov/33539477/Cell Biology
Telomeric double-strand DNA-binding proteins DTN-1 and DTN-2 ensure germline immortality in Caenorhabditis elegans
https://pubmed.ncbi.nlm.nih.gov/33476260/Cell Biology
The focal adhesion protein Testin modulates KCNE2 potassium channel β subunit activity
https://www.tandfonline.com/doi/pdf/10.1080/19336950.2021.1874119Cancer Research
The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008504#sec013Cell Biology
Centriolar distal appendages activate the centrosome-PIDDosome-p53 signalling axis via ANKRD26
https://pubmed.ncbi.nlm.nih.gov/33350486/Cancer Research
Phosphorylation of PLCγ1 by EphA2 Receptor Tyrosine Kinase Promotes Tumor Growth in Lung Cancer
https://pubmed.ncbi.nlm.nih.gov/32753469/Plant Biology
TCMP-2 affects tomato flowering and interacts with BBX16, a homolog of the arabidopsis B-box MiP1b
https://pubmed.ncbi.nlm.nih.gov/33204936/Neuroscience
Novel phospho-switch function of delta-catenin in dendrite development
https://pubmed.ncbi.nlm.nih.gov/33007084/Plant Biology
At3g53630 encodes a GUN1-interacting protein under norflurazon treatment
https://pubmed.ncbi.nlm.nih.gov/33108535/Plant Biology
A small secreted protein from Zymoseptoria tritici interacts with a wheat E3 ubiquitin to promote disease
https://pubmed.ncbi.nlm.nih.gov/33095257/Plant Biology
Key role of the motor protein Kinesin 13B in the activity of homeodomain-leucine zipper I transcription factors
https://pubmed.ncbi.nlm.nih.gov/32882705/Cell Biology
A comparison of three approaches for the discovery of novel tripartite attachment complex proteins in Trypanosoma brucei
https://pubmed.ncbi.nlm.nih.gov/32936798/Cell Biology
Newly identified Gon4l/Udu-interacting proteins implicate novel functions.
https://pubmed.ncbi.nlm.nih.gov/32848183/Cancer Research
Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
https://pubmed.ncbi.nlm.nih.gov/32846126/Plant Biology
Glutaredoxin AtGRXS8 represses transcriptional and developmental responses to nitrate in Arabidopsis thaliana roots
https://pubmed.ncbi.nlm.nih.gov/32537558/Cell Biology
Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation
https://pubmed.ncbi.nlm.nih.gov/32437351/Cell Biology
PUB11-Dependent Ubiquitination of the Phospholipid Flippase ALA10 Modifies ALA10 Localization and Affects the Pool of Linolenic Phosphatidylcholine
https://pubmed.ncbi.nlm.nih.gov/32760418/Plant Biology
FRA1 Kinesin Modulates the Lateral Stability of Cortical Microtubules through Cellulose Synthase-Microtubule Uncoupling Proteins
https://pubmed.ncbi.nlm.nih.gov/32487563/Cell Biology
The Set1 N-terminal domain and Swd2 interact with RNA polymerase II CTD to recruit COMPASS
https://pubmed.ncbi.nlm.nih.gov/32358498/Cancer Research
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells
https://pubmed.ncbi.nlm.nih.gov/32345962/Cell Biology
Drosophila NUAK functions with Starvin/BAG3 in autophagic protein turnover
https://pubmed.ncbi.nlm.nih.gov/32320396/Neuroscience
Ankyrin Is An Intracellular Tether for TMC Mechanotransduction Channels
https://pubmed.ncbi.nlm.nih.gov/32325031/Cell Biology
Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity
https://pubmed.ncbi.nlm.nih.gov/32238831/Cell Biology
Disease-associated synaptic scaffold protein CNK2 modulates PSD size and influences localisation of the regulatory kinase TNIK
https://pubmed.ncbi.nlm.nih.gov/32235845/Cell Biology
APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin
https://pubmed.ncbi.nlm.nih.gov/32187552/Microbiology - Virology
Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion
https://www.ncbi.nlm.nih.gov/pubmed/32047127Cell Biology
A Novel Combined Scientific and Artistic Approach for the Advanced Characterization of Interactomes: The Akirin/Subolesin Model
https://pubmed.ncbi.nlm.nih.gov/32046307/Microbiology - Virology
Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection
https://www.ncbi.nlm.nih.gov/pubmed/31992623Cell Biology
TMEM98 is a negative regulator of FRAT mediated Wnt/ß-catenin signalling
https://www.ncbi.nlm.nih.gov/pubmed/31961879Virology
PAPD5/7 Are Host Factors That Are Required for Hepatitis B Virus RNA Stabilization
https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.30329Nanobodies
Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth.
https://pubmed.ncbi.nlm.nih.gov/33357422/Cell Biology
PAK Kinases Target Sortilin and Modulate Its Sorting
https://www.ncbi.nlm.nih.gov/pubmed/31767632Nanobodies
Development and characterization of single-domain antibodies neutralizing protease nexin-1 as tools to increase thrombin generation.
https://pubmed.ncbi.nlm.nih.gov/32495984/Nanobodies
Structural basis for the dominant or recessive character of GLIALCAM mutations found in leukodystrophies
https://pubmed.ncbi.nlm.nih.gov/31960914/Nanobodies
Single-domain antibodies for functional targeting of the signaling scaffold Shoc2
https://pubmed.ncbi.nlm.nih.gov/31869742/Nanobodies
Single Domain Antibody Fragments as New Tools for the Detection of Neuronal Tau Protein in Cells and in Mice Studies
https://pubs.acs.org/doi/10.1021/acschemneuro.9b00217Nanobodies
NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies
https://elifesciences.org/articles/16228Cell Biology
Two-hybrid screening of FAM13A protein partners in lung epithelial cells
https://www.ncbi.nlm.nih.gov/pubmed/31900205Development
TBX1 is required for normal stria vascularis and semicircular canal development
https://www.ncbi.nlm.nih.gov/pubmed/31550482Cancer Research
Annexin A6 improves anti-migratory and anti-invasive properties of tyrosine kinase inhibitors in EGFR overexpressing human squamous epithelial cells
https://www.ncbi.nlm.nih.gov/pubmed/31869496Microbiology - Virology
Ubiquitination of Listeria Virulence Factor InlC Contributes to the Host Response to Infection
https://www.ncbi.nlm.nih.gov/pubmed/?term=10.1128%2FmBio.02778-19Immunology
Interleukin-38 interacts with destrin/actin-depolymerizing factor in human keratinocytes
https://www.ncbi.nlm.nih.gov/pubmed/31770407Neuroscience
FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation
https://www.ncbi.nlm.nih.gov/pubmed/31541015Neuroscience
Identification of HIVEP2 as a dopaminergic transcription factor related to substance use disorders in rats and humans. Transl Psychiatry
https://www.ncbi.nlm.nih.gov/pubmed/31586043Immunology
TRIM58 Restrains Intestinal Mucosal Inflammation by Negatively Regulating TLR2 in Myeloid Cells
https://www.ncbi.nlm.nih.gov/pubmed/31383741Cell Biology
lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites
https://www.ncbi.nlm.nih.gov/pubmed/31492901Cell Biology
A kinetochore-based ATM/ATR-independent DNA damage checkpoint maintains genomic integrity in trypanosomes
https://www.ncbi.nlm.nih.gov/pubmed/31147720Cell Biology
The novel cyclophilin-D-interacting protein FASTKD1 protects cells against oxidative stress-induced cell death
https://www.ncbi.nlm.nih.gov/pubmed/31268778Development
An actin-based viscoplastic lock ensures progressive body-axis elongation
https://www.ncbi.nlm.nih.gov/pubmed/31462781Cell Biology
SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation
https://www.ncbi.nlm.nih.gov/pubmed/?term=31519521Neuroscience
HENA, heterogeneous network-based data set for Alzheimer's disease
https://www.ncbi.nlm.nih.gov/pubmed/31413325Cell Biology
A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production
https://pubmed.ncbi.nlm.nih.gov/31398345/Microbiology - Virology
KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides
https://www.ncbi.nlm.nih.gov/pubmed/31284899Plant Biology
Bipartite anchoring of SCREAM enforces stomatal initiation by coupling MAP kinases to SPEECHLESS
https://www.ncbi.nlm.nih.gov/pubmed/31235876Cell Biology
Slx5/Slx8-dependent ubiquitin hotspots on chromatin contribute to stress tolerance
https://www.ncbi.nlm.nih.gov/pubmed/31015336Neuroscience
VCP/p97 controls signals of the ERK1/2 pathway transmitted via the Shoc2 scaffolding complex: novel insights into IBMPFD pathology
https://www.ncbi.nlm.nih.gov/pubmed/31091164Neuroscience
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus
https://www.ncbi.nlm.nih.gov/pubmed/31086297Cell Biology
The mouse intron-nested gene, Israa, is expressed in the lymphoid organs and involved in T-cell activation and signaling
https://www.ncbi.nlm.nih.gov/pubmed/31096062Neuroscience
Csmd2 Is a Synaptic Transmembrane Protein that Interacts with PSD-95 and Is Required for Neuronal Maturation
https://www.ncbi.nlm.nih.gov/pubmed/31073541Cell Biology
Identification of transmembrane protein 237 as a novel interactor with the intestinal riboflavin transporter-3 (RFVT-3): role in functionality and cell biology
https://www.ncbi.nlm.nih.gov/pubmed/30892938Cell Biology
FKBP12: A partner of Snx10 required for vesicular trafficking in osteoclasts
https://www.ncbi.nlm.nih.gov/pubmed/30887568Plant Biology
A wheat NAC interacts with an orphan protein and enhances resistance to Fusarium head blight disease
https://www.ncbi.nlm.nih.gov/pubmed/30821405?report=abstractCell Biology
Rho-family GTPase 1 (Rnd1) is a biomechanical stress-sensitive activator of cardiomyocyte hypertrophy
https://www.ncbi.nlm.nih.gov/pubmed/30797814Plant Biology
GmZPR3d Interacts with GmHD-ZIP III Proteins and Regulates Soybean Root and Nodule Vascular Development
https://www.ncbi.nlm.nih.gov/pubmed/30769886Cancer Research
A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination
https://www.ncbi.nlm.nih.gov/pubmed/30760716Microbiology - Virology
Shigella IpaA Binding to Talin Stimulates Filopodial Capture and Cell Adhesion
https://www.ncbi.nlm.nih.gov/pubmed/30673614Development
The apical protein Apnoia interacts with Crumbs to regulate tracheal growth and inflation
https://www.ncbi.nlm.nih.gov/pubmed/30645584Cell Biology
Headcase and Unkempt Regulate Tissue Growth and Cell Cycle Progression in Response to Nutrient Restriction
https://www.ncbi.nlm.nih.gov/pubmed/30650363Plant Biology
PII1: a protein involved in starch initiation that determines granule number and size in Arabidopsis chloroplast
https://www.ncbi.nlm.nih.gov/pubmed/30055112Development
salto/CG13164 is required for sperm head morphogenesis in Drosophila
https://www.ncbi.nlm.nih.gov/pubmed/30601696Immunology
NLRP10 Affects the Stability of Abin-1 To Control Inflammatory Responses
https://www.ncbi.nlm.nih.gov/pubmed/30510071Cell Biology
The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans
https://www.ncbi.nlm.nih.gov/pubmed/30567997Immunology
Grainyhead-like-2 confers NK-sensitivity through interactions with epigenetic modifier
https://www.ncbi.nlm.nih.gov/pubmed/30508726Microbiology - Virology
Multiple components of the nuclear pore complex interact with the amino-terminus of MX2 to facilitate HIV-1 restriction
https://www.ncbi.nlm.nih.gov/pubmed/30496303Neuroscience
The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21
https://www.ncbi.nlm.nih.gov/pubmed/30485814Plant Biology
Proteasome-associated HECT-type ubiquitin ligase activity is required for plant immunity
https://www.ncbi.nlm.nih.gov/pubmed/30458055Plant Biology
A common genetic mechanism underlies morphological diversity in fruits and other plant organs
https://www.ncbi.nlm.nih.gov/pubmed/30413711Neuroscience
ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome
https://www.ncbi.nlm.nih.gov/pubmed/30352948Cell Biology
PiT1/Slc20a1 is required for endoplasmic reticulum homeostasis, chondrocyte survival and skeletal development
https://www.ncbi.nlm.nih.gov/pubmed/30347511Microbiology - Virology
Characterization of a Toxoplasma effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation
https://www.ncbi.nlm.nih.gov/pubmed/30320549Cell Biology
Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3
https://www.ncbi.nlm.nih.gov/pubmed/30150681Cell Biology
NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
https://www.ncbi.nlm.nih.gov/pubmed/30270045Cell Biology
Fam49/CYRI interacts with Rac1 and locally suppresses protrusions
https://www.ncbi.nlm.nih.gov/pubmed/30250061Cancer Research
VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX
https://www.ncbi.nlm.nih.gov/pubmed/30285739Plant Biology
Arabidopsis Protein Kinase D6PKL3 Is Involved in the Formation of Distinct Plasma Membrane Aperture Domains on the Pollen Surface
https://www.ncbi.nlm.nih.gov/pubmed/30150313Cell Biology
A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export
https://www.ncbi.nlm.nih.gov/pubmed/30249596Cancer Research
The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer
https://www.ncbi.nlm.nih.gov/pubmed/30480076Cell Biology
Integrating Rio1 activities discloses its nutrient-activated network in Saccharomyces cerevisiae
https://www.ncbi.nlm.nih.gov/pubmed/30011030Plant Biology
Phosphorylation of Arabidopsis SINA2 by CDKG1 affects its ubiquitin ligase activity
https://www.ncbi.nlm.nih.gov/pubmed/30012094Cell Biology
A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links
https://www.ncbi.nlm.nih.gov/pubmed/29968717Cell Biology
Interactions between monomeric CCTδ and p150Glued: A novel function for CCTδ at the cell periphery distinct from the protein folding activity of the molecular chaperone CCT
https://www.ncbi.nlm.nih.gov/pubmed/29913154Microbiology - Virology
Lmo1656 is a secreted virulence factor of Listeria monocytogenes that interacts with the sorting nexin 6-BAR complex
https://pubmed.ncbi.nlm.nih.gov/29666193/Neuroscience
LPS-Induced Inflammation Abolishes the Effect of DYRK1A on IkB Stability in the Brain of Mice
https://www.ncbi.nlm.nih.gov/pubmed/29850989Cell Biology
The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones
https://www.ncbi.nlm.nih.gov/pubmed/29844425Plant Biology
Leptosphaeria maculans Effector Protein AvrLm1 Modulates Plant Immunity by Enhancing MAP Kinase 9 Phosphorylation
https://www.cell.com/iscience/abstract/S2589-0042(18)30047-6Cell Biology
Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families
https://www.ncbi.nlm.nih.gov/pubmed/29758265Cancer Research
Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth
https://www.ncbi.nlm.nih.gov/pubmed/29750782Microbiology - Virology
Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria
https://www.ncbi.nlm.nih.gov/pubmed/29746835Cell Biology
Disentangling the molecular determinants for Cenp-F localization to nuclear pores and kinetochores
https://www.ncbi.nlm.nih.gov/pubmed/29632243Neuroscience
The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin
https://www.ncbi.nlm.nih.gov/pubmed/29534157Microbiology - Virology
Ehrlichia chaffeensis TRP75 Interacts with Host Cell Targets Involved in Homeostasis, Cytoskeleton Organization, and Apoptosis Regulation To Promote Infection
https://www.ncbi.nlm.nih.gov/pubmed/29643078Cell Biology
The MT-CO1 V83I Polymorphism is a Risk Factor for Primary Open-Angle Glaucoma in African American Men
https://www.ncbi.nlm.nih.gov/pubmed/29610859Cell Biology
The apical scaffold big bang binds to spectrins and regulates the growth of Drosophila melanogaster wing discs
https://www.ncbi.nlm.nih.gov/pubmed/29326287Plant Biology
The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor
https://www.ncbi.nlm.nih.gov/pubmed/29217772Plant Biology
A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi
https://www.ncbi.nlm.nih.gov/pubmed/29363594Cell Biology
Repression of Cell Differentiation by a cis-Acting lincRNA in Fission Yeast
https://www.ncbi.nlm.nih.gov/pubmed/29395921Plant Biology
Members of the DEAL subfamily of the DUF1218 gene family are required for bilateral symmetry but not for dorsoventrality in Arabidopsis leaves
https://www.ncbi.nlm.nih.gov/pubmed/29139551Metabolism
A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy
https://www.ncbi.nlm.nih.gov/pubmed/28339911Cell Biology
A mechanism for epigenetic control of DNA replication
https://www.ncbi.nlm.nih.gov/pubmed/29483155Cancer Research
SILAC identifies LAD1 as a filamin-binding regulator of actin dynamics in response to EGF and a marker of aggressive breast tumors
https://www.ncbi.nlm.nih.gov/pubmed/29382783Plant Biology
Potato mop-top virus co-opts the stress sensor HIPP26 for long-distance movement
https://www.ncbi.nlm.nih.gov/pubmed/29374107Cancer Research
A caspase-2-RFXANK interaction and its implication for MHC class II expression
https://www.ncbi.nlm.nih.gov/pubmed/29362422Microbiology - Virology
Human adenovirus infection causes the cellular MKRN1 E3 ubiquitin ligase degradation involving the viral core protein pVII
https://www.ncbi.nlm.nih.gov/pubmed/29142133Neuroscience
miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons
https://www.ncbi.nlm.nih.gov/pubmed/29180574Cell Biology
Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function
https://www.ncbi.nlm.nih.gov/pubmed/29183906Cell Biology
Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles
https://www.ncbi.nlm.nih.gov/pubmed/29229865Cell Biology
The PRDM9 KRAB domain is required for meiosis and involved in protein interactions
https://www.ncbi.nlm.nih.gov/pubmed/28527011Cell Biology
Drosophila protein phosphatases 2A B' Wdb and Wrd regulate meiotic centromere localization and function of the MEI-S332 Shugoshin
https://www.ncbi.nlm.nih.gov/pubmed/29158400Cell Biology
Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects
https://www.ncbi.nlm.nih.gov/pubmed/29127204Immunology
Orientia tsutsugamushi modulates endoplasmic reticulum-associated degradation to benefit its growth
https://www.ncbi.nlm.nih.gov/pubmed/29109174Cell Biology
Selenoprotein T is a novel OST subunit that regulates UPR signaling and hormone secretion
https://www.ncbi.nlm.nih.gov/pubmed/28928140Microbiology - Virology
OrfX, a Nucleomodulin Required for Listeria monocytogenes Virulence
https://www.ncbi.nlm.nih.gov/pubmed/29089430Microbiology - Virology
Efficient invasion by Toxoplasma depends on the subversion of host protein networks
https://www.ncbi.nlm.nih.gov/pubmed/28848228Immunology
The Scaffolding Protein IQGAP1 Interacts with NLRC3 and Inhibits Type I IFN Production
https://www.ncbi.nlm.nih.gov/pubmed/28864474Neuroscience
The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex
https://www.ncbi.nlm.nih.gov/pubmed/28641386Cell Biology
Golgi-Resident Gαo Promotes Protrusive Membrane Dynamics
https://www.ncbi.nlm.nih.gov/pubmed/28803726Neuroscience
Protein kinase C regulates AMPA receptor auxiliary protein Shisa9/CKAMP44 through interactions with neuronal scaffold PICK1
https://www.ncbi.nlm.nih.gov/pubmed/28904854Cell Biology
Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP
https://www.ncbi.nlm.nih.gov/pubmed/28602823Cell Biology
Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP
https://www.ncbi.nlm.nih.gov/pubmed/28680062Microbiology - Virology
A Pseudomonas aeruginosa TIR effector mediates immune evasion by targeting UBAP1 and TLR adaptors
https://www.ncbi.nlm.nih.gov/pubmed/28483816Development
Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division
https://www.ncbi.nlm.nih.gov/pubmed/28665270Cancer Research
Interactions between mitoNEET and NAF-1 in cells
https://www.ncbi.nlm.nih.gov/pubmed/28426722Cell Biology
Binding and inhibition of the ternary complex factor Elk-4/Sap1 by the adapter protein Dok-4
https://www.ncbi.nlm.nih.gov/pubmed/28275114Plant Biology
Coordination of Meristem Doming and the Floral Transition by Late Termination, a Kelch Repeat Protein
https://www.ncbi.nlm.nih.gov/pubmed/28389586Immunology
STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling
https://www.ncbi.nlm.nih.gov/pubmed/28165510Microbiology - Virology
Cell Cycle-independent Role of Cyclin D3 in Host Restriction of Influenza Virus Infection
https://www.ncbi.nlm.nih.gov/pubmed/28130444Cancer Research
Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56
https://www.ncbi.nlm.nih.gov/pubmed/28174209Cell Biology
Interactome of the inhibitory isoform of the nuclear transporter Importin 13
https://www.ncbi.nlm.nih.gov/pubmed/27993670Cell Biology
TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury
https://www.ncbi.nlm.nih.gov/pubmed/28256593Immunology
Armc5 deletion causes developmental defects and compromises T-cell immune responses
https://www.ncbi.nlm.nih.gov/pubmed/28169274Plant Biology
NBP35 interacts with DRE2 in the maturation of cytosolic iron-sulphur proteins in Arabidopsis thaliana
https://www.ncbi.nlm.nih.gov/pubmed/27801963Cell Biology
Harnessing molecular motors for nanoscale pulldown in live cells
https://www.ncbi.nlm.nih.gov/pubmed/27932498Cell Biology
Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16
https://www.ncbi.nlm.nih.gov/pubmed/28128203Cell Biology
The In Vivo Architecture of the Exocyst Provides Structural Basis for Exocytosis
https://www.ncbi.nlm.nih.gov/pubmed/28129539Plant Biology
The DC1-domain protein VACUOLELESS GAMETOPHYTES is essential for development of female and male gametophytes in Arabidopsis
https://www.ncbi.nlm.nih.gov/pubmed/28107777Microbiology - Virology
Orientia tsutsugamushi Ank9 is a multifunctional effector that utilizes a novel GRIP-like Golgi localization domain for Golgi-to-endoplasmic reticulum trafficking and interacts with host COPB2
https://www.ncbi.nlm.nih.gov/pubmed/28103630Cell Biology
Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection
https://www.ncbi.nlm.nih.gov/pubmed/28063255Cell Biology
Endospanin1 affects oppositely body weight regulation and glucose homeostasis by differentially regulating central leptin signaling
https://www.ncbi.nlm.nih.gov/pubmed/28123946Immunology
Tartrate-Resistant Acid Phosphatase Deficiency in the Predisposition to Systemic Lupus Erythematosus
https://www.ncbi.nlm.nih.gov/pubmed/27390188Plant Biology
Plant-specific 4/1 polypeptide interacts with an endoplasmic reticulum protein related to human BAP31
https://www.ncbi.nlm.nih.gov/pubmed/27714454Cancer Research
Wnt Signaling Promotes Breast Cancer by Blocking ITCH-Mediated Degradation of YAP/TAZ Transcriptional Coactivator WBP2
https://www.ncbi.nlm.nih.gov/pubmed/27578003Cell Biology
(hors ligne car publi de Valérie) Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase
https://www.ncbi.nlm.nih.gov/pubmed/27693059Neuroscience
MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density
https://www.ncbi.nlm.nih.gov/pubmed/27756895Plant Biology
Regulation of MIR165/166 by class II and class III homeodomain leucine zipper proteins establishes leaf polarity
https://www.ncbi.nlm.nih.gov/pubmed/27698117Microbiology - Virology
The DUF582 Proteins of Chlamydia trachomatis Bind to Components of the ESCRT Machinery, Which Is Dispensable for Bacterial Growth In vitro
https://www.ncbi.nlm.nih.gov/pubmed/27774439Cell Biology
Direct interaction between exocyst and Wave complexes promotes cell protrusions and motility
https://www.ncbi.nlm.nih.gov/pubmed/27591259Plant Biology
Control of inflorescence architecture in tomato by BTB/POZ transcriptional regulators
https://www.ncbi.nlm.nih.gov/pubmed/27798848Cell Biology
DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk
https://www.ncbi.nlm.nih.gov/pubmed/27614019Cell Biology
The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs
https://www.ncbi.nlm.nih.gov/pubmed/27605379Cell Biology
Disruption of the Phosphate Transporter Pit1 in Hepatocytes Improves Glucose Metabolism and Insulin Signaling by Modulating the USP7/IRS1 Interaction
https://www.ncbi.nlm.nih.gov/pubmed/27568561Cell Biology
Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase
http://www.ncbi.nlm.nih.gov/pubmed/27397685Cell Biology
Wars2 is a determinant of angiogenesis
http://www.ncbi.nlm.nih.gov/pubmed/27389904Cell Biology
FAM222B Is Not a Likely Novel Candidate Gene for Cerebral Cavernous Malformations
https://www.ncbi.nlm.nih.gov/pubmed/27587990Cell Biology
The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2
https://www.ncbi.nlm.nih.gov/pubmed/27068743Microbiology - Virology
Definition of the cellular interactome of the highly pathogenic avian influenza H5N1 virus: identification of human cellular regulators of viral entry, assembly, and egress
https://www.ncbi.nlm.nih.gov/pubmed/27390003Plant Biology
[ hors ligne car on a pas fait les manips ] Golgi-localized STELLO proteins regulate the assembly and trafficking of cellulose synthase complexes in Arabidopsis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906169/Cancer Research
Setdb1, a novel interactor of? Np63, is involved in breast tumorigenesis
https://www.ncbi.nlm.nih.gov/pubmed/26840455Microbiology - Virology
Staphylococcal Enterotoxin O Exhibits Cell Cycle Modulating Activity
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832122/Cell Biology
Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening
http://www.ncbi.nlm.nih.gov/pubmed/27040773Cell Biology
PLEKHA7 recruits PDZD11 to adherens junctions to stabilize nectins
http://www.ncbi.nlm.nih.gov/pubmed/27044745Neuroscience
Nuclear Localization of the Autism Candidate Gene Neurobeachin and Functional Interaction with the NOTCH1 Intracellular Domain Indicate a Role in Regulating Transcription
http://www.ncbi.nlm.nih.gov/pubmed/26999814Cell Biology
Identification of new FGF1 binding partners-Implications for its intracellular function
http://www.ncbi.nlm.nih.gov/pubmed/26840910Cancer Research
NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells
http://www.ncbi.nlm.nih.gov/pubmed/26948053Microbiology - Virology
The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells
http://www.ncbi.nlm.nih.gov/pubmed/26924733Cell Biology
BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation
http://www.ncbi.nlm.nih.gov/pubmed/26912148Neuroscience
CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization
http://www.ncbi.nlm.nih.gov/pubmed/26849555Cell Biology
Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs
https://www.ncbi.nlm.nih.gov/pubmed/26845027Plant Biology
PP2A-3 interacts with ACR4 and regulates formative cell division in the Arabidopsis root
https://www.ncbi.nlm.nih.gov/pubmed/26792519Neuroscience
Post-translational Control of the Temporal Dynamics of Transcription Factor Activity Regulates Neurogenesis
https://www.ncbi.nlm.nih.gov/pubmed/26824657Cell Biology
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin
https://www.ncbi.nlm.nih.gov/pubmed/26816381Neuroscience
Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons
https://www.ncbi.nlm.nih.gov/pubmed/26514267Cell Biology
A novel family of katanin-like 2 protein isoforms (KATNAL2), interacting with nucleotide-binding proteins Nubp1 and Nubp2, are key regulators of different MT-based processes in mammalian cells
https://www.ncbi.nlm.nih.gov/pubmed/26153462Cell Biology
Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5
https://www.ncbi.nlm.nih.gov/pubmed/26519477Plant Biology
TaFROG Encodes a Pooideae Orphan Protein That Interacts with SnRK1 and Enhances Resistance to the Mycotoxigenic Fungus Fusarium graminearum
https://www.ncbi.nlm.nih.gov/pubmed/26508775Plant Biology
Regulation of Carotenoid Biosynthesis by Shade Relies on Specific Subsets of Antagonistic Transcription Factors and Cofactors
https://www.ncbi.nlm.nih.gov/pubmed/26082398Cell Biology
Role of the Exocyst Complex Component Sec6/8 in Genomic Stability
https://www.ncbi.nlm.nih.gov/pubmed/26283729Cell Biology
Unresolved questions in human copper pump mechanisms
https://www.ncbi.nlm.nih.gov/pubmed/26537407Development
The Brakeless co-regulator can directly activate and repress transcription in early Drosophila embryos
https://www.ncbi.nlm.nih.gov/pubmed/26260775Cell Biology
Cystatin D Locates in the Nucleus at Sites of Active Transcription and Modulates Gene and Protein Expression
https://www.ncbi.nlm.nih.gov/pubmed/26364852Development
Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton
https://www.ncbi.nlm.nih.gov/pubmed/26506308Plant Biology
Universal stress protein HRU1 mediates ROS homeostasis under anoxia
https://www.ncbi.nlm.nih.gov/pubmed/27251529Cell Biology
The Pro-apoptotic STK38 Kinase Is a New Beclin1 Partner Positively Regulating Autophagy
http://www.ncbi.nlm.nih.gov/pubmed/26387716Cell Biology
Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins
http://www.ncbi.nlm.nih.gov/pubmed/26420826Cancer Research
Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells
http://www.ncbi.nlm.nih.gov/pubmed/26183398Neuroscience
The Q-Soluble-N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor (Q-SNARE) SNAP-47 Regulates Trafficking of Selected Vesicle-Associated Membrane Proteins (VAMPs)
http://www.ncbi.nlm.nih.gov/pubmed/26359495Cell Biology
MVP-Associated Filamin A Mutations Affect FlnA-PTPN12 (PTP-PEST) Interactions
https://www.ncbi.nlm.nih.gov/pubmed/26594644Development
Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish
https://www.ncbi.nlm.nih.gov/pubmed/26335201Cancer Research
AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis
https://www.ncbi.nlm.nih.gov/pubmed/26079538Cell Biology
A potential link between insulin signaling and GLUT4 translocation: Association of Rab10-GTP with the exocyst subunit Exoc6/6b
http://www.ncbi.nlm.nih.gov/pubmed/26299925Neuroscience
A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones
https://www.ncbi.nlm.nih.gov/pubmed/26274777Cell Biology
Identification of New Potential Interaction Partners for Human Cytoplasmic Copper Chaperone Atox1: Roles in Gene Regulation?
http://www.ncbi.nlm.nih.gov/pubmed/26213915Neuroscience
Ctr9, a Protein in the Transcription Complex Paf1, Regulates Dopamine Transporter Activity at the Plasma Membrane
http://www.ncbi.nlm.nih.gov/pubmed/26048990Cancer Research
Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to Hydrogen peroxide-induced oxidative stress in Human hepatobiliary Cancer cells
http://www.ncbi.nlm.nih.gov/pubmed/26169728Cell Biology
Loss of apoptosis-inducing factor critically affects MIA40 function
http://www.ncbi.nlm.nih.gov/pubmed/26158520Cell Biology
HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity
http://www.ncbi.nlm.nih.gov/pubmed/26147758Plant Biology
The Interactome of Soybean GmWRKY53 using Yeast 2-Hybrid Library Screening to Saturation
http://www.ncbi.nlm.nih.gov/pubmed/26102586Plant Biology
Arabidopsis KCBP interacts with AIR9 but stays in the cortical division zone throughout mitosis via its MyTH4-FERM domain
https://www.ncbi.nlm.nih.gov/pubmed/25908862Cell Biology
Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells
http://www.ncbi.nlm.nih.gov/pubmed/25986860Cell Biology
Alpha-catenin-dependent recruitment of the centrosomal protein CAP350 to adherens junctions allows epithelial cells to acquire a columnar shape
http://www.ncbi.nlm.nih.gov/pubmed/25764135Cell Biology
Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC
http://www.ncbi.nlm.nih.gov/pubmed/25818646Microbiology - Virology
The membrane protein PrsS mimics sigmaS in protecting Staphylococcus aureus against cell wall-targeting antibiotics and DNA-damaging agents
http://www.ncbi.nlm.nih.gov/pubmed/25741016Cell Biology
DNA damage-induced nuclear translocation of Apaf-1 is mediated by nucleoporin Nup107
https://www.ncbi.nlm.nih.gov/pubmed/25695197Cancer Research
TGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesis
http://www.ncbi.nlm.nih.gov/pubmed/%2025873176Cell Biology
Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation
http://www.ncbi.nlm.nih.gov/pubmed/25851096Plant Biology
Time-dependent sequestration of RVE8 by LNK proteins shapes the diurnal oscillation of anthocyanin biosynthesis
http://www.ncbi.nlm.nih.gov/pubmed/25848001Cell Biology
Interactome of the negative regulator of nuclear import BRCA1-binding protein 2
https://www.ncbi.nlm.nih.gov/pubmed/25820252Cell Biology
The Fun30 chromatin remodeler Fft3 controls nuclear organization and chromatin structure of insulators and subtelomeres in fission yeast
http://www.ncbi.nlm.nih.gov/pubmed/25798942Development
Drosophila MAGI interacts with RASSF8 to regulate E-Cadherin-based adherens junctions in the developing eye
http://www.ncbi.nlm.nih.gov/pubmed/25725070Cancer Research
The Tumor Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the Beta-catenin Coactivator BCL9-2 in Breast Cancer Cells
http://www.ncbi.nlm.nih.gov/pubmed/25678599Cell Biology
Spectrin binding motifs regulate Scribble cortical dynamics and polarity function
http://www.ncbi.nlm.nih.gov/pubmed/25664942Neuroscience
Linking Cell Surface Receptors to Microtubules: Tubulin Folding Cofactor D Mediates Dscam Functions during Neuronal Morphogenesis
http://www.ncbi.nlm.nih.gov/pubmed/25653356Cell Biology
Supervillin binds the Rac/Rho-GEF trio and increases trio-mediated rac1 activation
http://www.ncbi.nlm.nih.gov/pubmed/25655724Neuroscience
Control of neuronal apoptosis by reciprocal regulation of NFATc3 and Trim17
https://www.ncbi.nlm.nih.gov/pubmed/25215946Neuroscience
Oligodendroglial maturation is dependent on intracellular protein shuttling
http://www.ncbi.nlm.nih.gov/pubmed/25609610Cell Biology
Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle
http://www.ncbi.nlm.nih.gov/pubmed/25605665Microbiology - Virology
The integrase cofactor LEDGF/p75 associates with Iws1 and Spt6 for postintegration silencing of HIV-1 gene expression in latently infected cells
http://www.ncbi.nlm.nih.gov/pubmed/25590759Plant Biology
Arabidopsis AIP1-2 restricted by WER-mediated patterning modulates planar polarity
https://www.ncbi.nlm.nih.gov/pubmed/25428588Microbiology - Virology
SUMOylation by the E3 ligase TbSIZ1/PIAS1 positively regulates VSG expression in Trypanosoma brucei
https://www.ncbi.nlm.nih.gov/pubmed/25474309Cell Biology
The eukaryotic elongation factor eEF1A1 interacts with SAMHD1
http://www.ncbi.nlm.nih.gov/pubmed/25423367Plant Biology
Association of the P6 protein of Cauliflower mosaic virus with plasmodesmata and plasmodesmal proteins
https://www.ncbi.nlm.nih.gov/pubmed/25239023Development
Drosophila Strip serves as a platform for early endosome organization during axon elongation
https://www.ncbi.nlm.nih.gov/pubmed/25312435Cancer Research
RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789
https://www.ncbi.nlm.nih.gov/pubmed/24141780Cell Biology
HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold
http://www.ncbi.nlm.nih.gov/pubmed/25022756Development
Heterotrimeric Go protein links Wnt-Frizzled signaling with ankyrins to regulate the neuronal microtubule cytoskeleton
http://www.ncbi.nlm.nih.gov/pubmed/25139856Plant Biology
PIRIN2 stabilizes cysteine protease XCP2 and increases susceptibility to the vascular pathogen Ralstonia solanacearum in Arabidopsis
http://www.ncbi.nlm.nih.gov/pubmed/24947605Cell Biology
DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia
https://www.ncbi.nlm.nih.gov/pubmed/25009281Plant Biology
Functional characterisation of Arabidopsis SPL7 conserved protein domains suggests novel regulatory mechanisms in the Cu deficiency response
https://www.ncbi.nlm.nih.gov/pubmed/25207797Cell Biology
The RING ubiquitin E3 RNF114 interacts with A20 and modulates NF-κB activity and T-cell activation
https://www.ncbi.nlm.nih.gov/pubmed/25165885Cell Biology
Remodeling of the Intestinal Brush Border Underlies Adhesion and Virulence of an Enteric Pathogen
http://www.ncbi.nlm.nih.gov/pubmed/25139905Microbiology - Virology
The PDZ-Binding Motif of Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Is a Determinant of Viral Pathogenesis
http://www.ncbi.nlm.nih.gov/pubmed/25122212Neuroscience
Plasma DYRK1A as a novel risk factor for Alzheimer's disease
http://www.ncbi.nlm.nih.gov/pubmed/25116835Cell Biology
SPEG Interacts with Myotubularin, and Its Deficiency Causes Centronuclear Myopathy with Dilated Cardiomyopathy
https://www.ncbi.nlm.nih.gov/pubmed/25087613Cell Biology
Gαs regulates the post-endocytic sorting of G protein-coupled receptors
https://www.ncbi.nlm.nih.gov/pubmed/25089012Cell Biology
Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity
http://www.ncbi.nlm.nih.gov/pubmed/25064856Cell Biology
FHOD1 interaction with nesprin-2G mediates TAN line formation and nuclear movement
http://www.ncbi.nlm.nih.gov/pubmed/24880667Neuroscience
Lysosome size, motility and stress response regulated by fronto-temporal dementia modifier TMEM106B
https://www.ncbi.nlm.nih.gov/pubmed/25066864Cell Biology
The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration
http://www.ncbi.nlm.nih.gov/pubmed/24841562Plant Biology
Expression of a Truncated ATHB17 Protein in Maize Increases Ear Weight at Silking
http://www.ncbi.nlm.nih.gov/pubmed/24736658Cell Biology
Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells
http://www.ncbi.nlm.nih.gov/pubmed/24814316Cell Biology
Src kinases and ERK activate distinct responses to Stitcher receptor tyrosine kinase signaling during wound healing in Drosophila
http://www.ncbi.nlm.nih.gov/pubmed/24522188Cell Biology
New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens
http://www.ncbi.nlm.nih.gov/pubmed/24714733Plant Biology
Phytoplasma effector SAP54 hijacks plant reproduction by degrading MADS-box proteins and promotes insect colonization in a RAD23-dependent manner
http://www.ncbi.nlm.nih.gov/pubmed/24714165Cell Biology
The SNARE Sec22b has a non-fusogenic function in plasma membrane expansion
http://www.ncbi.nlm.nih.gov/pubmed/24705552Cell Biology
Apm4, the mu subunit of yeast AP-2 interacts with Pkc1, and mutation of the Pkc1 consensus phosphorylation site Thr176 inhibits AP-2 recruitment to endocytic sites
http://www.ncbi.nlm.nih.gov/pubmed/25346786Cell Biology
Proteins Associated with SF3a60 in T. brucei
http://www.ncbi.nlm.nih.gov/pubmed/24651488Cell Biology
Association of TM4SF4 with the human thiamine transporter-2 in intestinal epithelial cells
http://www.ncbi.nlm.nih.gov/pubmed/24282057Development
A Complex Regulatory Network Coordinating Cell Cycles During Caenorhabditis elegans Development Is Revealed by a Genome-Wide RNAi Screen
http://www.ncbi.nlm.nih.gov/pubmed/24584095Cell Biology
G-protein coupled receptor BAI3 promotes myoblast fusion in vertebrates
http://www.ncbi.nlm.nih.gov/pubmed/24567399Plant Biology
A Conserved KIN17 Curved DNA-Binding Domain Protein Assembles with SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE7 to Adapt Arabidopsis Growth and Development to Limiting Copper Availability
http://www.ncbi.nlm.nih.gov/pubmed/24335506Cancer Research
Metastasis suppressor KISS1 seems to reverse the Warburg effect by enhancing mitochondrial biogenesis
https://www.ncbi.nlm.nih.gov/pubmed/25207797Cell Biology
DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity
http://www.ncbi.nlm.nih.gov/pubmed/24473148Plant Biology
Pathogen and Circadian Controlled 1 (PCC1) Protein Is Anchored to the Plasma Membrane and Interacts with Subunit 5 of COP9 Signalosome in Arabidopsis
http://www.ncbi.nlm.nih.gov/pubmed/24475254Cell Biology
Plakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activity
https://www.ncbi.nlm.nih.gov/pubmed/24475179Development
The C. elegans LC3 Acts Downstream of GABARAP to Degrade Autophagosomes by Interacting with the HOPS Subunit VPS39
http://www.ncbi.nlm.nih.gov/pubmed/24374177Development
Brain tumor specifies intermediate progenitor cell identity by attenuating β-catenin/Armadillo activity
http://www.ncbi.nlm.nih.gov/pubmed/24257623Cell Biology
The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes
http://www.ncbi.nlm.nih.gov/pubmed/24211586Cell Biology
The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling
https://www.ncbi.nlm.nih.gov/pubmed/25485589Cancer Research
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia
http://www.ncbi.nlm.nih.gov/pubmed/24344185Plant Biology
XRN4 and LARP1 are required for a heat-triggered mRNA decay pathway involved in plant acclimation and survival during thermal stress
https://www.ncbi.nlm.nih.gov/pubmed/24332370Cell Biology
Identification of Global Ferredoxin Interaction Networks in Chlamydomonas reinhardtii
http://www.ncbi.nlm.nih.gov/pubmed/24100040Neuroscience
PRICKLE1 Interaction with SYNAPSIN I Reveals a Role in Autism Spectrum Disorders
http://www.ncbi.nlm.nih.gov/pubmed/24312498Microbiology - Virology
The chlamydial OTU domain-containing protein ChlaOTU is an early type III secretion effector targeting ubiquitin and NDP52
https://www.ncbi.nlm.nih.gov/pubmed/23869922Cell Biology
Rab4b controls an early endosome sorting event by interacting with the γ-subunit of the clathrin adaptor complex 1
http://www.ncbi.nlm.nih.gov/pubmed/24006255Plant Biology
Arabidopsis J-Protein J20 Delivers the First Enzyme of the Plastidial Isoprenoid Pathway to Protein Quality Control
http://www.ncbi.nlm.nih.gov/pubmed/24104567Cancer Research
RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789
http://www.ncbi.nlm.nih.gov/pubmed/24141780Cancer Research
Ribosomal Proteins RPL37, RPS15 and RPS20 Regulate the Mdm2-p53-MdmX Network
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068667Microbiology - Virology
HIV-1 Vpr Induces the Degradation of ZIP and sZIP, Adaptors of the NuRD Chromatin Remodeling Complex, by Hijacking DCAF1/VprBP
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0077320Neuroscience
Silencing of doublecortin-like (DCL) results in decreased mitochondrial activity and delayed neuroblastoma tumor growth
http://www.ncbi.nlm.nih.gov/pubmed/24086625Cancer Research
The Dependence Receptor TrkC Triggers Mitochondria-Dependent Apoptosis upon Cobra-1 Recruitment
http://www.ncbi.nlm.nih.gov/pubmed/24034695Cancer Research
HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells
http://www.ncbi.nlm.nih.gov/pubmed?term=23045287Development
TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity
http://www.ncbi.nlm.nih.gov/pubmed/23671695Cell Biology
The guanine nucleotide exchange factor Rlf interacts with SH3 domain-containing proteins via a binding site with a preselected conformation
https://www.ncbi.nlm.nih.gov/pubmed/23891840Cell Biology
Microtubule severing by the katanin complex is activated by PPFR-1-dependent MEI-1 dephosphorylation
http://www.ncbi.nlm.nih.gov/pubmed/23918937Cell Biology
Coiled-Coil Domain Containing Protein 124 Is a Novel Centrosome and Midbody Protein That Interacts with the Ras-Guanine Nucleotide Exchange Factor 1B and Is Involved in Cytokinesis
http://www.ncbi.nlm.nih.gov/pubmed/23894443Neuroscience
Shootin1 Acts in Concert with KIF20B to Promote Polarization of Migrating Neurons
http://www.ncbi.nlm.nih.gov/pubmed/23864681Neuroscience
LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortex
https://www.ncbi.nlm.nih.gov/pubmed/23844656Plant Biology
Trans-Golgi Network Localized ECHIDNA/Ypt Interacting Protein Complex Is Required for the Secretion of Cell Wall Polysaccharides in Arabidopsis
http://www.ncbi.nlm.nih.gov/pubmed/23832588Cell Biology
FAM190A deficiency creates a cell division defect
http://www.ncbi.nlm.nih.gov/pubmed/23665203Cell Biology
Functional Integration of the Conserved Domains of Shoc2 Scaffold
http://www.ncbi.nlm.nih.gov/pubmed/23805200Plant Biology
The P6 protein of Cauliflower mosaic virus interacts with CHUP1, a plant protein which moves chloroplasts on actin microfilaments
http://www.ncbi.nlm.nih.gov/pubmed/23769239Plant Biology
The bHLH proteins BEE and BIM positively modulate the shade avoidance syndrome in Arabidopsis seedlings
http://www.ncbi.nlm.nih.gov/pubmed/23763263Cell Biology
A New Mint1 Isoform, but Not the Conventional Mint1, Interacts with the Small GTPase Rab6
http://www.ncbi.nlm.nih.gov/pubmed/23737971Cell Biology
Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression
http://www.ncbi.nlm.nih.gov/pubmed/23345399Plant Biology
Negative Feedback Control of Jasmonate Signaling by an Alternative Splice Variant of JAZ10
http://www.ncbi.nlm.nih.gov/pubmed/23632853Development
The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins
http://www.ncbi.nlm.nih.gov/pubmed/23707952Neuroscience
Dock3 interaction with a glutamate-receptor NR2D subunit protects neurons from excitotoxicity
http://www.ncbi.nlm.nih.gov/pubmed/23641686Cell Biology
Biosynthesis of the urease metallocenter
http://www.ncbi.nlm.nih.gov/pubmed/23539618%0D%0DCell Biology
Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis
http://www.ncbi.nlm.nih.gov/pubmed/23599041Development
Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains
http://www.ncbi.nlm.nih.gov/pubmed/23479640Cell Biology
BANK1 and BLK Act through Phospholipase C Gamma 2 in B-Cell Signaling
http://www.ncbi.nlm.nih.gov/pubmed/23555801Cancer Research
Nuclear alpha1-antichymotrypsin promotes chromatin condensation and inhibits proliferation of human hepatocellular carcinoma cells
https://www.ncbi.nlm.nih.gov/pubmed/23295442Cell Biology
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
http://www.ncbi.nlm.nih.gov/pubmed/23414517Cell Biology
Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB
http://www.ncbi.nlm.nih.gov/pubmed/23477725Plant Biology
CLASP Interacts with Sorting Nexin 1 to Link Microtubules and Auxin Transport via PIN2 Recycling in Arabidopsis thaliana
http://www.ncbi.nlm.nih.gov/pubmed/23477787Cell Biology
Conundrum, an ARHGAP18 orthologue, regulates RhoA and proliferation through interactions with Moesin
http://www.ncbi.nlm.nih.gov/pubmed/23468526Plant Biology
Identification of SHRUBBY, a SHORT-ROOT and SCARECROW interacting protein that controls root growth and radial patterning
http://www.ncbi.nlm.nih.gov/pubmed/23444357Cancer Research
Lysine methylation of VCP by a member of a novel human protein methyltransferase family
http://www.ncbi.nlm.nih.gov/pubmed/22948820Cell Biology
ELMO recruits Actin Crosslinking Family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions
http://www.ncbi.nlm.nih.gov/pubmed/23184944Cell Biology
The COMPASS Subunit Spp1 Links Histone Methylation to Initiation of Meiotic Recombination
http://www.ncbi.nlm.nih.gov/pubmed/23160953Immunology
Fam65b Is a New Transcriptional Target of FOXO1 That Regulates RhoA Signaling for T Lymphocyte Migration
http://www.ncbi.nlm.nih.gov/pubmed/23241886Cell Biology
Identification of novel interacting partners of sirtuin6
http://www.ncbi.nlm.nih.gov/pubmed/23240041Microbiology - Virology
Ezrin Interacts with the SARS Coronavirus Spike Protein and Restrains Infection at the Entry Stage
http://www.ncbi.nlm.nih.gov/pubmed/23185364Plant Biology
The Ubiquitin Ligase PUB22 Targets a Subunit of the Exocyst Complex Required for PAMP-Triggered Responses in Arabidopsis
http://www.ncbi.nlm.nih.gov/pubmed/23170036Plant Biology
Arabidopsis thaliana AUCSIA-1 regulates auxin biology and physically interacts with a kinesin-related protein
http://www.ncbi.nlm.nih.gov/pubmed/22911780Cell Biology
Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
http://www.ncbi.nlm.nih.gov/pubmed/23139756Cell Biology
Human ALKBH4 Interacts with Proteins Associated with Transcription
http://www.ncbi.nlm.nih.gov/pubmed/23145062Plant Biology
Synchronization of the flowering transition by the tomato TERMINATING FLOWER gene
http://www.ncbi.nlm.nih.gov/pubmed/23143603Development
Integration of Kinase and Phosphatase Activities by BUBR1 Ensures Formation of Stable Kinetochore-Microtubule Attachments
http://www.ncbi.nlm.nih.gov/pubmed?term=23079597Cancer Research
Iodide Transporter NIS Regulates Cancer Cell Motility and Invasiveness by Interacting with the Rho Guanine Nucleotide Exchange Factor LARG
http://www.ncbi.nlm.nih.gov/pubmed/22962269Cancer Research
Novel mechanism of apoptosis resistance in cancer mediated by extracellular PAR-4
https://pubmed.ncbi.nlm.nih.gov/23204231/Cancer Research
The transcription factor CREBZF is a novel positive regulator of p53
http://www.ncbi.nlm.nih.gov/pubmed/22983008Development
Numb/Numbl-Opo Antagonism Controls Retinal Epithelium Morphogenesis by Regulating Integrin Endocytosis
http://www.ncbi.nlm.nih.gov/pubmed/23041384Cell Biology
New insights into Dok-4 PTB domain structure and function
http://www.ncbi.nlm.nih.gov/pubmed/22982678Cell Biology
A Molecular Network for the Transport of the TI-VAMP/VAMP7 Vesicles from Cell Center to Periphery
http://www.ncbi.nlm.nih.gov/pubmed/22705394Cell Biology
A meckelin-filamin A interaction mediates ciliogenesis
http://www.ncbi.nlm.nih.gov/pubmed/22121117Cancer Research
Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins
http://www.ncbi.nlm.nih.gov/pubmed/22315224Cell Biology
Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation
http://www.ncbi.nlm.nih.gov/pubmed/22433841Cell Biology
Rab8a regulates the exocyst-mediated kiss-and-run discharge of the Dictyostelium contractile vacuole
http://www.ncbi.nlm.nih.gov/pubmed/22323285Microbiology - Virology
Ex Vivo and In Vivo Inhibition of Human Rhinovirus Replication by a New Pseudosubstrate of Viral 2A Protease
http://www.ncbi.nlm.nih.gov/pubmed/22072773Microbiology - Virology
Human annexin a6 interacts with influenza a virus protein m2 and negatively modulates infection
http://www.ncbi.nlm.nih.gov/pubmed/22114333Development
MAP and kinesin-dependent nuclear positioning is required for skeletal muscle function
http://www.ncbi.nlm.nih.gov/pubmed/22425998Cell Biology
Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis
http://www.ncbi.nlm.nih.gov/pubmed/22184064Cell Biology
Pex3-anchored Atg36 tags peroxisomes for degradation in Saccharomyces cerevisiae
http://www.ncbi.nlm.nih.gov/pubmed/22643220Plant Biology
Involvement of the N-terminal B-box domain of Arabidopsis BBX32 in interacting with soybean BBX62
http://www.ncbi.nlm.nih.gov/pubmed/22801428Microbiology - Virology
Respiratory syncytial virus assembles into structured filamentous virion particles independently of host cytoskeleton and related proteins
http://www.ncbi.nlm.nih.gov/pubmed/22808269Cell Biology
Ezrin ubiquitylation by the E3 ubiquitin ligase, WWP1, and consequent regulation of hepatocyte growth factor receptor activity
http://www.ncbi.nlm.nih.gov/pubmed/22629406Cell Biology
Ezrin regulates microvillus morphogenesis by promoting distinct activities of Eps8 proteins
http://www.ncbi.nlm.nih.gov/pubmed/22262457Plant Biology
A j-like protein influences Fatty Acid composition of chloroplast lipids in Arabidopsis
http://www.ncbi.nlm.nih.gov/pubmed/22028775Cell Biology
Fukutin-related protein resides in the Golgi cisternae of skeletal muscle fibres and forms disulfide-linked homodimers via an N-terminal interaction
http://www.ncbi.nlm.nih.gov/pubmed/21886772Cell Biology
BetaArrestin 1 inhibits the GAP function of ARHGAP21 so as to promote the activation of RhoA following angiotensin II type 1A receptor stimulation
http://www.ncbi.nlm.nih.gov/pubmed/21173159Cell Biology
Interaction between nucleosome assembly protein 1-like family members
http://www.ncbi.nlm.nih.gov/pubmed/21333655Cell Biology
RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly
http://www.ncbi.nlm.nih.gov/pubmed/21241894Cell Biology
A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase
http://www.ncbi.nlm.nih.gov/pubmed/21383080Cell Biology
The ERM proteins interact with the class C-Vps/HOPS complex to regulate the maturation of endosomes
http://www.ncbi.nlm.nih.gov/pubmed/21148287Microbiology - Virology
Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import
http://www.ncbi.nlm.nih.gov/pubmed/22176773Cell Biology
Inhibition of autophagy by TAB2 and TAB3
http://www.ncbi.nlm.nih.gov/pubmed/22081109Cell Biology
Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis
http://www.ncbi.nlm.nih.gov/pubmed/21706022Microbiology - Virology
Recruitment of the Major Vault Protein by InlK: A Listeria monocytogenes Strategy to Avoid Autophagy
http://www.ncbi.nlm.nih.gov/pubmed/21829365Microbiology - Virology
Characterization of the elongasome core PBP2 : MreC complex of Helicobacter pylori
http://www.ncbi.nlm.nih.gov/pubmed/21801243Metabolism
Teashirt-3, a novel regulator of muscle differentiation, associates with BRG-1 associated factor 57 (BAF57) to inhibit myogenin gene expression
http://www.ncbi.nlm.nih.gov/pubmed/21543328Microbiology - Virology
Fusobacterium nucleatum adhesin FadA binds vascular-endothelial cadherin and alters endothelial integrity
http://www.ncbi.nlm.nih.gov/pubmed/22040113Cell Biology
The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity
http://www.ncbi.nlm.nih.gov/pubmed/21670213Cell Biology
Caspase-3 cleavage links delta-catenin to the novel nuclear protein ZIFCAT
http://www.ncbi.nlm.nih.gov/pubmed/21561870Microbiology - Virology
ATF3, an HTLV-1 bZip factor binding protein, promotes proliferation of adult T-cell leukemia cells
http://www.ncbi.nlm.nih.gov/pubmed/21414204Metabolism
Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle
http://www.ncbi.nlm.nih.gov/pubmed/21135508Cell Biology
A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition
http://www.ncbi.nlm.nih.gov/pubmed/21746881Microbiology - Virology
A Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response
http://www.ncbi.nlm.nih.gov/pubmed/21252314Metabolism
Novel interactions of ankyrins-G at the costameres: The muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C
http://www.ncbi.nlm.nih.gov/pubmed/21223964Plant Biology
The Tomato MADS-Box Transcription Factor RIPENING INHIBITOR Interacts with Promoters Involved in Numerous Ripening Processes in a COLORLESS NONRIPENING-Dependent Manner
http://www.ncbi.nlm.nih.gov/pubmed/21941001Cell Biology
Association of PDZ-containing protein PDZD11 with the human sodium-dependent multivitamin transporter
http://www.ncbi.nlm.nih.gov/pubmed/21183659Cancer Research
TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation
http://www.ncbi.nlm.nih.gov/pubmed/21329883Cell Biology
SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility
http://www.ncbi.nlm.nih.gov/pubmed/21658605Cell Biology
The Arf family GTPase, Arl4A, complexes with ELMO to promote actin cytoskeleton remodeling and reveals a versatile Ras-Binding Domain in the ELMO protein family
http://www.ncbi.nlm.nih.gov/pubmed/21930703Cell Biology
A role for ZO-1 and PLEKHA7 in recruiting paracingulin to tight and adherens junctions of epithelial cells
http://www.ncbi.nlm.nih.gov/pubmed/21454477Cell Biology
The involvement of SMILE/TMTC3 in endoplasmic reticulum stress response
http://www.ncbi.nlm.nih.gov/pubmed/21603654Development
Regulation of Drosophila glial cell proliferation by Merlin-Hippo signaling
http://www.ncbi.nlm.nih.gov/pubmed/22069188Cancer Research
A Tumor-Associated Mutation of FYVE-CENT Prevents Its Interaction with Beclin 1 and Interferes with Cytokinesis
http://www.ncbi.nlm.nih.gov/pubmed/21455500Cell Biology
ERBIN is a new SARA-interacting protein: competition between SARA and SMAD2 and SMAD3 for binding to ERBIN
http://www.ncbi.nlm.nih.gov/pubmed/21878490Metabolism
UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting
http://www.ncbi.nlm.nih.gov/pubmed/21757351Plant Biology
Phytoplasma protein effector SAP11 enhances insect vector reproduction by manipulating plant development and defense hormone biosynthesis
http://www.ncbi.nlm.nih.gov/pubmed/22065743Cancer Research
Regulation of PIDD auto-proteolysis and activity by the molecular chaperone Hsp90
http://www.ncbi.nlm.nih.gov/pubmed/20966961Plant Biology
O-glycosylated cell wall proteins are essential in root hair growth
http://www.ncbi.nlm.nih.gov/pubmed/21680836Microbiology - Virology
Escherichia coli producing CNF1 toxin hijacks Tollip to trigger Rac1-dependent cell invasion
http://www.ncbi.nlm.nih.gov/pubmed/21291504Neuroscience
The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function
http://www.ncbi.nlm.nih.gov/pubmed/20838393Development
The Enhancer of split transcription factor Her8a is a novel dimerisation partner for Her3 that controls anterior hindbrain neurogenesis in zebrafish
http://www.ncbi.nlm.nih.gov/pubmed/21586122Microbiology - Virology
A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3067920Cell Biology
La-related protein 4 binds poly(A), interacts with the poly(A)-binding protein MLLE domain via a variant PAM2w motif, and can promote mRNA stability
http://www.ncbi.nlm.nih.gov/pubmed/21098120Cancer Research
Increased RNA-Induced Silencing Complex (RISC) Activity Contributes to Hepatocellular Carcinoma
http://www.ncbi.nlm.nih.gov/pubmed/21520169Cell Biology
Interaction of the receptor FGFRL1 with the negative regulator Spred1
http://www.ncbi.nlm.nih.gov/pubmed/21616146Immunology
Tripartite motif containing protein 27 negatively regulates CD4 T cells by ubiquitinating and inhibiting the class II PI3K-C2Beta
http://www.ncbi.nlm.nih.gov/pubmed/22128329Neuroscience
Disrupted-in-Schizophrenia 1-mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling
http://www.ncbi.nlm.nih.gov/pubmed/21422296Cell Biology
A screen for deubiquitinating enzymes involved in the G(2)/M checkpoint identifies USP50 as a regulator of HSP90-dependent Wee1 stability
http://www.ncbi.nlm.nih.gov/pubmed/20930503Development
The WW domain protein Kibra acts upstream of Hippo in Drosophila
http://www.ncbi.nlm.nih.gov/pubmed/20159600Plant Biology
PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors
http://www.ncbi.nlm.nih.gov/pubmed/19962994Cell Biology
Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins
http://www.ncbi.nlm.nih.gov/pubmed/19864490Cell Biology
Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity
http://www.ncbi.nlm.nih.gov/pubmed/21062899Cell Biology
Functional interaction between the ubiquitin-specific protease 25 and the SYK tyrosine kinase
http://www.ncbi.nlm.nih.gov/pubmed/19909739Metabolism
Lack of Apobec2-related proteins causes a dystrophic muscle phenotype in zebrafish embryos
http://www.ncbi.nlm.nih.gov/pubmed/20440001Plant Biology
Arabidopsis thaliana GYRB3 does not encode a DNA gyrase subunit
http://www.ncbi.nlm.nih.gov/pubmed/20360860Cell Biology
LRCH proteins: a novel family of cytoskeletal regulators
http://www.ncbi.nlm.nih.gov/pubmed/20805893Cell Biology
Kibra is a regulator of the Salvador/Warts/Hippo signaling network
http://www.ncbi.nlm.nih.gov/pubmed/20159599Metabolism
Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins
http://www.ncbi.nlm.nih.gov/pubmed/20855527Microbiology - Virology
The Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the IkappaB kinase subunit IKKalpha
http://www.ncbi.nlm.nih.gov/pubmed/20855622Plant Biology
Identification of a cellulose synthase-associated protein required for cellulose biosynthesis
http://www.ncbi.nlm.nih.gov/pubmed/20616083Cell Biology
Sip1, the Drosophila orthologue of EBP50/NHERF1, functions with the sterile 20 family kinase Slik to regulate Moesin activity
http://www.ncbi.nlm.nih.gov/pubmed/20215404Microbiology - Virology
Pathogenic bacteria target NEDD8-conjugated cullins to hijack host-cell signaling pathways
http://www.ncbi.nlm.nih.gov/pubmed/20941356Microbiology - Virology
The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication
http://www.ncbi.nlm.nih.gov/pubmed/20345489Cell Biology
The SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt
http://www.ncbi.nlm.nih.gov/pubmed/20148946Cell Biology
Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes
http://www.ncbi.nlm.nih.gov/pubmed/20174469Cell Biology
Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I
http://www.ncbi.nlm.nih.gov/pubmed/20562214Cancer Research
A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin
http://www.ncbi.nlm.nih.gov/pubmed/20888340Plant Biology
A Host-Factor Interaction and Localization Map for a Plant-Adapted Rhabdovirus Implicates Cytoplasm-Tethered Transcription Activators in Cell-to-Cell Movement
http://www.ncbi.nlm.nih.gov/pubmed/20923350Cell Biology
Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex
http://www.ncbi.nlm.nih.gov/pubmed/20562865Plant Biology
Interaction of a plant pseudo-response regulator with a calmodulin-like protein
http://www.ncbi.nlm.nih.gov/pubmed/20627089Neuroscience
Cytosolic protein interactions of the schizophrenia susceptibility gene dysbindin
http://www.ncbi.nlm.nih.gov/pubmed/20236384Neuroscience
Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin
http://www.ncbi.nlm.nih.gov/pubmed/20880836Neuroscience
Neuregulin-1 modulates the differentiation of neural stem cells in vitro trough an interaction with the Swi/Snf complex
http://www.ncbi.nlm.nih.gov/pubmed/19781646Microbiology - Virology
Attenuation of rabies virulence: takeover by the cytoplasmic domain of its envelope protein
http://www.ncbi.nlm.nih.gov/pubmed/20086240Cancer Research
Differential regulation of HIC1 target genes by CtBP and NuRD, via an Acetylation/SUMOylation switch, in quiescent versus proliferating cells
http://www.ncbi.nlm.nih.gov/pubmed/20547755Plant Biology
The nuclear interactor PYL8/RCAR3 of Fagus sylvatica FsPP2C1 is a positive regulator of abscisic acid signaling in seeds and stress
http://www.ncbi.nlm.nih.gov/pubmed/19889877Cell Biology
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
http://www.ncbi.nlm.nih.gov/pubmed/20208530Metabolism
Interactions with M-band titin and calpain 3 link myospryn (CMYA5) to tibial and limb-girdle muscular dystrophies
http://www.ncbi.nlm.nih.gov/pubmed/20634290Development
Inhibition of the nuclear import of cubitus interruptus by roadkill in the presence of strong hedgehog signal
http://www.ncbi.nlm.nih.gov/pubmed/21179535Neuroscience
A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation
http://www.ncbi.nlm.nih.gov/pubmed/20080956Cell Biology
Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding
http://www.ncbi.nlm.nih.gov/pubmed/20123966Microbiology - Virology
The SARS Coronavirus E Protein Interacts with PALS1 and Alters Tight Junction Formation and Epithelial Morphogenesis
http://www.ncbi.nlm.nih.gov/pubmed/20861307Cancer Research
GAM/ZFp/ZNF512B is central to a gene sensor circuitry involving cell-cycle regulators, TGFbeta effectors, Drosha and microRNAs with opposite oncogenic potentials
http://www.ncbi.nlm.nih.gov/pubmed/20639536Neuroscience
Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development
http://www.ncbi.nlm.nih.gov/pubmed/20685985Cell Biology
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
http://www.ncbi.nlm.nih.gov/pubmed/20159598Neuroscience
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1
http://www.ncbi.nlm.nih.gov/pubmed/20139976Microbiology - Virology
Molecular interaction of flagellar export chaperone FliS and cochaperone HP1076 in Helicobacter pylori
https://www.ncbi.nlm.nih.gov/pubmed/20581225Cell Biology
MidA is a putative methyltransferase that is required for mitochondrial complex I function
http://www.ncbi.nlm.nih.gov/pubmed/20406883Immunology
Characterization of single chain antibody targets through yeast two hybrid
http://www.ncbi.nlm.nih.gov/pubmed/20727208Microbiology - Virology
Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ
http://www.ncbi.nlm.nih.gov/pubmed/19244240Cancer Research
Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein
http://www.ncbi.nlm.nih.gov/pubmed/19465938Neuroscience
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212
http://www.ncbi.nlm.nih.gov/pubmed/19778506Neuroscience
An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures
http://www.ncbi.nlm.nih.gov/pubmed/18986647Cell Biology
Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex
http://www.ncbi.nlm.nih.gov/pubmed/19386264Cancer Research
Functional genomic screens identify CINP as a genome maintenance protein
http://www.ncbi.nlm.nih.gov/pubmed/19889979Cancer Research
Calcineurin a-binding protein, a novel modulator of the calcineurin-nuclear factor of activated T-cell signaling pathway, is overexpressed in wilms' tumors and promotes cell migration
http://www.ncbi.nlm.nih.gov/pubmed/19531566Cancer Research
HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A
http://www.ncbi.nlm.nih.gov/pubmed/19486893Cancer Research
The antiapoptotic protein AAC-11 interacts with and regulates Acinus-mediated DNA fragmentation
http://www.ncbi.nlm.nih.gov/pubmed/19387494Cell Biology
An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation
http://www.ncbi.nlm.nih.gov/pubmed/19885391Neuroscience
Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses
https://www.ncbi.nlm.nih.gov/pubmed/19744958Cell Biology
Udu deficiency activates DNA damage checkpoint
http://www.ncbi.nlm.nih.gov/pubmed?term=19656853Cell Biology
Mint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1
https://www.ncbi.nlm.nih.gov/pubmed/19726677Cancer Research
The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks
http://www.ncbi.nlm.nih.gov/pubmed/19793861Immunology
A function for AAMP in Nod2-mediated NF-kappaB activation
http://www.ncbi.nlm.nih.gov/pubmed/19535145Cell Biology
Human BAHD1 promotes heterochromatic gene silencing
http://www.ncbi.nlm.nih.gov/pubmed/19666599Neuroscience
Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth
http://www.ncbi.nlm.nih.gov/pubmed/19745841Cell Biology
Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton
www.ncbi.nlm.nih.gov/pubmed/19596800Cell Biology
A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome
http://www.ncbi.nlm.nih.gov/pubmed/19661920Cell Biology
Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome
http://www.ncbi.nlm.nih.gov/pubmed/19854871Neuroscience
GPR50 interacts with neuronal NOGO-A and affects neurite outgrowth
http://www.ncbi.nlm.nih.gov/pubmed/19699797Cell Biology
Drosophila GoLoco-protein Pins is a target of Galpha(o)-mediated G protein-coupled receptor signaling.
http://www.ncbi.nlm.nih.gov/pubmed/19570914Cancer Research
MSK2 inhibits p53 activity in the absence of stress
http://www.ncbi.nlm.nih.gov/pubmed/19797274Cell Biology
The membrane-tubulating potential of amphiphysin 2/BIN1 is dependent on the microtubule-binding cytoplasmic linker protein 170 (CLIP-170)
http://www.ncbi.nlm.nih.gov/pubmed/19004523Cell Biology
ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis
http://www.ncbi.nlm.nih.gov/pubmed/19211056Cell Biology
Septins regulate bacterial entry into host cells
http://www.ncbi.nlm.nih.gov/pubmed/19145258Microbiology - Virology
Identification of TRIM23 as a cofactor involved in the regulation of NF-kappaB by human cytomegalovirus
http://www.ncbi.nlm.nih.gov/pubmed/19176615Cell Biology
Ribosomal protein S7 is both a regulator and a substrate of MDM2
https://www.ncbi.nlm.nih.gov/pubmed/19683495Cell Biology
hPOC5 is a centrin-binding protein required for assembly of full-length centrioles
http://www.ncbi.nlm.nih.gov/pubmed/19349582Microbiology - Virology
Functional characterization and protein-protein interactions of trypanosome splicing factors U2AF35, U2AF65 and SF1
https://www.ncbi.nlm.nih.gov/pubmed/19320097Cell Biology
The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling
https://www.ncbi.nlm.nih.gov/pubmed/19131965Cell Biology
DLG1/SAP97 modulates transforming growth factor alpha bioavailability
https://www.ncbi.nlm.nih.gov/pubmed/18930083Neuroscience
Pro-apoptotic protein-protein interactions of the extended N-AChE terminus
https://www.ncbi.nlm.nih.gov/pubmed/19533292Cell Biology
Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector
https://www.ncbi.nlm.nih.gov/pubmed/19319189Cancer Research
The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression
http://www.ncbi.nlm.nih.gov/pubmed/17934516Cell Biology
Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1
http://www.ncbi.nlm.nih.gov/pubmed/18729074Neuroscience
Targeting of the 5-HT1A serotonin receptor to neuronal dendrites is mediated by Yif1B
http://www.ncbi.nlm.nih.gov/pubmed/18685031Cell Biology
Role of HRB in clathrin-dependent endocytosis
http://www.ncbi.nlm.nih.gov/pubmed/18819912Microbiology - Virology
Transportin-SR2 imports HIV into the nucleus
http://www.ncbi.nlm.nih.gov/pubmed/18722123Cancer Research
Identification of PCTA, a TGIF antagonist that promotes PML function in TGF-beta signalling
http://www.ncbi.nlm.nih.gov/pubmed/18511908Cell Biology
The PDZ protein mupp1 promotes Gi coupling and signaling of the Mt1 melatonin receptor
http://www.ncbi.nlm.nih.gov/pubmed/18378672Cell Biology
ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGFβ bioavailability regulation
http://www.ncbi.nlm.nih.gov/pubmed/18677313Microbiology - Virology
HuR interacts with human immunodeficiency virus type 1 reverse transcriptase, and modulates reverse transcription in infected cells
http://www.ncbi.nlm.nih.gov/pubmed/18544151Microbiology - Virology
AKAP149 binds to HIV-1 reverse transcriptase and is involved in the reverse transcription
http://www.ncbi.nlm.nih.gov/pubmed/18786546Cell Biology
Modification of Drosophila p53 by SUMO modulates its transactivation and pro-apoptotic functions
http://www.ncbi.nlm.nih.gov/pubmed/18492669Cell Biology
Spatial recruitment and activation of the Fes kinase by ezrin promotes HGF-induced cell scattering
http://www.ncbi.nlm.nih.gov/pubmed/18046454Neuroscience
Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR
http://www.ncbi.nlm.nih.gov/pubmed/18718938Microbiology - Virology
The Listeria monocytogenes virulence factor InlJ is specifically expressed in vivo and behaves as an adhesin
http://www.ncbi.nlm.nih.gov/pubmed/18227172Cell Biology
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA
http://www.ncbi.nlm.nih.gov/pubmed/18541705Cell Biology
The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor
http://www.ncbi.nlm.nih.gov/pubmed/17620406Microbiology - Virology
Identification of the LEDGF/p75 binding site in HIV-1 integrase
http://www.ncbi.nlm.nih.gov/pubmed/17137594Neuroscience
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
http://www.ncbi.nlm.nih.gov/pubmed/17043677Cell Biology
Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells
http://www.ncbi.nlm.nih.gov/pubmed/17881735Cell Biology
The Hsp40 chaperone Jjj1 is required for the nucleo-cytoplasmic recycling of preribosomal factors in Saccharomyces ce
http://www.ncbi.nlm.nih.gov/pubmed/17652132Development
Spermatocyte cytokinesis requires rapid membrane addition mediated by ARF6 on central spindle recycling endosomes
http://www.ncbi.nlm.nih.gov/pubmed/18039970Cancer Research
RASSF1C, an isoform of the tumor suppressor RASSF1A, promotes the accumulation of beta-catenin by interacting with betaTrCP
http://www.ncbi.nlm.nih.gov/pubmed/17283138Development
The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis
http://www.ncbi.nlm.nih.gov/pubmed/17586488Cell Biology
Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions
http://www.ncbi.nlm.nih.gov/pubmed/17666436Neuroscience
Interaction between telencephalin and ERM family proteins mediates dendritic filopodia formation
http://www.ncbi.nlm.nih.gov/pubmed/17699668Development
Rab6 and the secretory pathway affect oocyte polarity in Drosophila
http://www.ncbi.nlm.nih.gov/pubmed/17827179Cancer Research
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
http://www.ncbi.nlm.nih.gov/pubmed/17446862Development
The last 59 amino acids of Smoothened cytoplasmic tail directly bind the protein kinase Fused and negatively regulate the Hedgehog pathway
http://www.ncbi.nlm.nih.gov/pubmed/17182028Microbiology - Virology
von Hippel Lindau binding protein 1-mediated degradation of integrase affects HIV-1 gene expression at a postintegration step
http://www.ncbi.nlm.nih.gov/pubmed/17698809Cell Biology
Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients
http://www.ncbi.nlm.nih.gov/pubmed/17380155Cell Biology
The PI3K effector Arap3 interacts with the PI(3,4,5)P3 phosphatase SHIP2 in a SAM domain-dependent manner
http://www.ncbi.nlm.nih.gov/pubmed/17314030Microbiology - Virology
HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase
http://www.ncbi.nlm.nih.gov/pubmed/17314515Cell Biology
Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation
http://www.ncbi.nlm.nih.gov/pubmed/17380122Cell Biology
The inhibition of polo kinase by matrimony maintains G2 arrest in the meiotic cell cycle
http://www.ncbi.nlm.nih.gov/pubmed/18052611Cell Biology
The gamma-core motif correlates with antimicrobial activity in cysteine-containing kaliocin-1 originating from transferrins
http://www.ncbi.nlm.nih.gov/pubmed/17916323Cell Biology
The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions
http://www.ncbi.nlm.nih.gov/pubmed/17363900Cell Biology
Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs
https://www.ncbi.nlm.nih.gov/pubmed/16861225Development
The Ral/exocyst effector complex counters c-Jun N-terminal kinase-dependent apoptosis in Drosophila melanogaster
http://www.ncbi.nlm.nih.gov/pubmed/17000765Cell Biology
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
http://www.ncbi.nlm.nih.gov/pubmed/16964248Microbiology - Virology
Role for erbin in bacterial activation of Nod2
http://www.ncbi.nlm.nih.gov/pubmed/16714539Development
The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover
http://www.ncbi.nlm.nih.gov/pubmed/16980583Cancer Research
LMO4 can interact with Smad proteins and modulate transforming growth factor-beta signaling in epithelial cells
http://www.ncbi.nlm.nih.gov/pubmed/16331278Cell Biology
A functional network involved in the recycling of nucleocytoplasmic pre-60S factors
https://www.ncbi.nlm.nih.gov/pubmed/16651379Microbiology - Virology
Inhibition of early steps of HIV-1 replication by SNF5/Ini1
http://www.ncbi.nlm.nih.gov/pubmed/16772295Development
Interaction between Polo and BicD proteins links oocyte determination and meiosis control in Drosophila
http://www.ncbi.nlm.nih.gov/pubmed/16971474Metabolism
HSPA12B is predominantly expressed in endothelial cells and required for angiogenesis
http://www.ncbi.nlm.nih.gov/pubmed/16825593Neuroscience
Interaction between the vesicular glutamate transporter type 1 and endophilin A1, a protein essential for endocytosis
http://www.ncbi.nlm.nih.gov/pubmed/16606361Neuroscience
Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly
http://www.ncbi.nlm.nih.gov/pubmed/15590698Microbiology - Virology
Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication
http://www.ncbi.nlm.nih.gov/pubmed/15855167Neuroscience
PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa
http://www.ncbi.nlm.nih.gov/pubmed/15976448Cancer Research
Oncogenic tyrosine kinase of malignant hemopathy targets the centrosome
https://www.ncbi.nlm.nih.gov/pubmed/16103074Cancer Research
Protein interaction mapping: a Drosophila case study
http://www.ncbi.nlm.nih.gov/pubmed/15710747Microbiology - Virology
The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes
http://www.ncbi.nlm.nih.gov/pubmed/16162672Cell Biology
RNA degradation by the exosome is promoted by a nuclear polyadenylation complex
http://www.ncbi.nlm.nih.gov/pubmed/15935758Development
Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane
http://www.ncbi.nlm.nih.gov/pubmed/16224820Neuroscience
DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling
http://www.ncbi.nlm.nih.gov/pubmed/16293762Development
Regulation of Notch signalling by non-visual beta-arrestin
http://www.ncbi.nlm.nih.gov/pubmed/16284625Microbiology - Virology
Stable accumulation of sigma54 in Helicobacter pylori requires the novel protein HP0958
http://www.ncbi.nlm.nih.gov/pubmed/15968056Microbiology - Virology
HP0958 is an essential motility gene in Helicobacter pylori
http://www.ncbi.nlm.nih.gov/pubmed/15946806Microbiology - Virology
ARHGAP10 is necessary for alpha-catenin recruitment at adherens junctions and for Listeria invasion
http://www.ncbi.nlm.nih.gov/pubmed/16184169Cell Biology
A new yeast poly(A) polymerase complex involved in RNA quality control
http://www.ncbi.nlm.nih.gov/pubmed/15828860Neuroscience
Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders
http://www.ncbi.nlm.nih.gov/pubmed/14962739Cell Biology
Functional proteomics mapping of a human signaling pathway
http://www.ncbi.nlm.nih.gov/pubmed/15231748Microbiology - Virology
Biochemical characterization of protein complexes from the Helicobacter pylori protein interaction map: strategies for complex formation and evidence for novel interactions within type IV secretion systems
http://www.ncbi.nlm.nih.gov/pubmed/15133060Cancer Research
Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer
http://www.ncbi.nlm.nih.gov/pubmed/12477722Microbiology - Virology
KSHV vFLIP binds to IKK-gamma to activate IKK
http://www.ncbi.nlm.nih.gov/pubmed/12890756Cell Biology
Sequential protein association with nascent 60S ribosomal particles
https://www.ncbi.nlm.nih.gov/pubmed/12808088Cancer Research
hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan
http://www.ncbi.nlm.nih.gov/pubmed/12592373Cell Biology
A dual mechanism controlling the localization and function of exocytic v-SNAREs
http://www.ncbi.nlm.nih.gov/pubmed/12853575Cell Biology
Identification and characterization of a novel RanGTP-binding protein in the yeast Saccharomyces cerevisiae
https://www.ncbi.nlm.nih.gov/pubmed/12578832Cell Biology
Ral GTPases regulate exocyst assembly through dual subunit interactions
http://www.ncbi.nlm.nih.gov/pubmed/14525976Neuroscience
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle
http://www.ncbi.nlm.nih.gov/pubmed/12485990Microbiology - Virology
Functional characterization of the antagonistic flagellar late regulators FliA and FlgM of Helicobacter pylori and their effects on the H. pylori transcriptome
http://www.ncbi.nlm.nih.gov/pubmed/11985711Microbiology - Virology
Identification of the Helicobacter pylori anti-sigma28 factor
http://www.ncbi.nlm.nih.gov/pubmed/11489132Microbiology - Virology
Characterization of the interaction partners of secreted proteins and chaperones of Shigella flexneri
http://www.ncbi.nlm.nih.gov/pubmed/11737652Microbiology - Virology
The protein-protein interaction map of Helicobacter pylori.
http://www.ncbi.nlm.nih.gov/pubmed/11196647Microbiology - Virology
A genomic approach of the hepatitis C virus generates a protein interaction map
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