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Nanobodies

Bivalent single-domain antibodies show potent mpox virus neutralization through M1R antigen

Daisuke Akazawa, Masayuki Shimojima, Eun-Sil Park, Akiko Okutani, Milagros Virhuez-Mendoza, Yusuke Inoue, Takayuki Hishiki, Ken Maeda, Hideki Ebihara, Yoshimasa Takahashi & Koichi Watashi

(2025) Communications Biology 8, 1073 (2025). https://doi.org/10.1038/s42003-025-08494-x

Microbiology - Cell Biology

A glyoxal-specific aldehyde signaling axis in Pseudomonas aeruginosa that influences quorum sensing and infection

Christopher J. Corcoran, Bonnie J. Cuthbert, David G. Glanville, Mailyn Terrado, Diana Valverde Mendez, Benjamin P. Bratton, Daniel E. Schemenauer, Valerie L. Tokars, Thomas G. Martin, Lawrence W. Rasmussen, Matthew C. Madison, Andrew F. Maule, Joshua W. Shaevitz, Boo Shan Tseng, Julian P. Whitelegge, Catherine Putonti, Amit Gaggar, Jordan R. Beach, Jonathan A. Kirk, Alfonso Mondragón, Abby R. Kroken, Jonathan P. Allen, Celia W. Goulding & Andrew T. Ulijasz

(2025) Nature Communications 16, 6616 (2025). https://doi.org/10.1038/s41467-025-61469-8

Molecular Biology - Cell Biology

A diverse interactome of the molecular chaperone CCT/TRiC monomers

Carmen M Córdoba-Beldad , Julie Grantham

(2025) European Journal of Cell Biology, 2025, 151506, ISSN 0171-9335, https://doi.org/10.1016/j.ejcb.2025.151506.

Nanobodies

Development and Use of a Galectin-1-Specific Nanobody for Tumor Imaging and Elucidating the Role of Galectin-1 in Cancer

Philippine Granger Joly de Boissel, Rita Nehmé, Marlène Fortier, Myriam Létourneau, Brigitte Guérin, Véronique Dumulon-Perreault, Samia Ait-Mohand, Otman Sarrhini, Camille Fuselier, Alyssa Dumoulin, David Chatenet, Nicolas Doucet, Yves St-Pierre

(2025) ACS Pharmacol. Transl. Sci. https://doi.org/10.1021/acsptsci.5c00178

Plant Biology - Microbiology

A Salivary Effector of the Pea Aphid Interacts with Pea Proteins and Enhances Its Performance on the Host Plant

Po-Yuan Shih, Stephanie Le Bras, Remi Ollivier, Helene Boulain, Stephanie Morliere, Yannick Outreman, Jean-Christophe Simon, and Akiko Sugio

(2025) APS Online Publications, https://doi.org/10.1094/MPMI-08-24-0089-R

Microbiology

The zinc metalloprotein MigC impacts cell wall biogenesis through interactions with an essential Mur ligase in Acinetobacter baumannii

Jeanette M. Critchlow ,Joseph S. Rocchio ,Melanie C. McKell,Courtney J. Campbell,Juan P. Barraza,Evan S. Krystofiak,Erin R. Green,Tae Akizuki,Walter J. Chazin,Michael S. VanNieuwenhze,Timothy L. Stemmler,David P. Giedroc ,Eric P. Skaar

(2025) PLoS Pathog 21(6): e1013209. https://doi.org/10.1371/journal.ppat.1013209

Development - Cell Biology

TANGO2 binds crystallin alpha B and its loss causes desminopathy

Maike Stentenbach, Laetitia A. Hughes, Samuel V. Fagan, Blake Payne, Danielle L. Rudler, Stefan J. Siira, Tim McCubbin, Anaëlle Chopin, Kara L. Perks, Judith A. Ermer, James Hendry, Teagan S. Er, Shanti Balasubramaniam, Joel A. Eliades, Livia C. Hool, Nicolle H. Packer, Edward S. X. Moh, Benjamin S. Padman, Oliver Rackham & Aleksandra Filipovska

(2025) Nature Communications volume 16, Article number: 5261, doi.org/10.1038/s41467-025-60563-1

Metabolism - Cell Biology

Searching for protein partners of short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD) reveals keratin 8 as a novel candidate for interaction in pancreatic β-cells

Kelly Velasco, Janniche Torsvik, Johanna L. St-Louis, Sarah Baghestani, Jonas S. G. Silvander, Rohit N. Kulkarni, Diana M. Toivola & Anders Molven

(2025) BMC Mol and Cell Biol 26, 18 . https://doi.org/10.1186/s12860-025-00544-w

Development - Cell Biology

The third intracellular loop of Drosophila Lilipod is required for protein function in vivo and can mediate protein-protein interactions in vitro

Merin Vellooparambil Roy, Scott J. Neal, Francesca Pignoni

(2025) Plos One, Published: June 4, https://doi.org/10.1371/journal.pone.0325326

Metabolism - Molecular Biology

Mitochondrial PTRH2 controls the deubiquitinase TRABID to regulate mt-ND5 stability and metabolism

Carlotta Giorgi, Femke J. Aan, Natalija Glibetic, Daniela Ramaccini, Lorenzo Modesti, Veronica A. M. Vitto, Vanessa Montoya-Uribe, Austin Corpuz, Sonia Missiroli, Inês Simões, Yaiza Potes, Mariusz R. Wieckowski, Joe W. Ramos, Paolo Pinton, and Michelle L. Matte

(2025) PNAS Nexus, pgaf178, https://doi.org/10.1093/pnasnexus/pgaf178

Development

PNUTS:PP1 recruitment to Tox4 regulates chromosomal dispersal in Drosophila germline development

Louise Duncalf, Xinru Wang, Abdulrahman A. Aljabri, Amy E. Campbell, Rawan Q. Alharbi, Ian Donaldson3 ∙ Andrew Hayes, Wolfgang Peti, Rebecca Page, Daimark Bennett

(2025) Cell Reports, Article Volume 44, Issue 5115693 May 27

Cell Biology - Plant Biology

Maize unstable factor for orange1 encodes a nuclear protein that affects redox accumulation during kernel development

Debamalya Chatterjee, Ziru Zhang, Pei-Yu Lin, Po-Hao Wang, Gurpreet K. Sidhu, Neela H. Yennawar, Jo-Wei Allison Hsieh, Pao-Yang Chen, Rentao Song, Blake C. Meyers, Surinder Chopra

(2025) The Plant Cell, 2025, 37, koae301 https://doi.org/10.1093/plcell/koae301