News-Events


LinkedIn page launch & 10% discount

May 14-June 15 - Paris, France

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Jean-Christophe Rain, general deputy manager, will give a seminar at the Promega Conference

May 28 - Paris, France

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Hybrigenics Services sponsors "le Colloque de la Société des Neurosciences Françaises" in Lyon

May 21-24 - Lyon, France

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Latest Publications


Dock3 interaction with a glutamate-receptor NR2D subunit protects neurons from excitotoxicity.

Bai N, Hayashi H, Aida T, Namekata K, Harada T, Mishina M, Tanaka K.

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Mechanism of repression by a JAZ10 splice variant

Gregg A. Howe

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Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains.

Bonner AM, Hughes SE, Chisholm JA, Smith SK, Slaughter BD, Unruh JR, Collins KA, Friederichs JM, Florens L, Swanson SK, Pelot MC, Miller DE, Washburn MP, Jaspersen SL, Hawley RS.

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BANK1 and BLK Act through Phospholipase C Gamma 2 in B-Cell Signaling

M. Bernal-Quiros, Ying-Yu Wu, M. E. Alarcon-Riquelme., C.Castillejo-Lopez

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A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

Blandin, G., Marchand, S., Charton, K., Danièle, N., Gicquel, E., Boucheteil, J.B., Bentaib, A., Barrault, L., Stockholm, D., Bartoli, M., and Richard, I.

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Testimonials


My interactions with the Hybrigenics team have been excellent. From the beginning of our collaboration involving library preparation through the point of completing two Y2H screens, the Hybrigenics...

Dr. Zach Lippman (CSHL, USA)
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Hybrigenics’ contribution to our HIV target identification and drug discovery programs was absolutely decisive. Thanks to their unparalleled Y2H technology, we discovered an interaction between a k...

Dr. Richard Benarous (Mutabilis, France)
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I learnt about Hybrigenics from a colleague who recommended this company warmly. Having performed several two-hybrid screens myself, I was very impressed by the professionalism at Hybrigenics. The ...

Pr. Harald Stenmark (University of Oslo, Norway)
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My laboratory carried out several screens with Hybrigenics in order to identify the partners of Rab GTPases, key regulators of intracellular traffic in eukaryotic cells. The results have been impre...

Dr. Bruno Goud (Institut Curie, France)
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I requested Hybrigenics to perform two yeast two hybrid screenings using both human and zebrafish gene. We could not set up to run in our lab due to cost, time and lack of zebrafish Y2H library. Th...

Dr. Tomoko Obara (University of Oklahoma Health Science Center, USA)
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We have enjoyed the interaction with the Hybrigenics team. They are professional, provided accurate and exciting results which lead our science to new frontiers. I recommended their services to ...

Dr. Orly Reiner (Weizmann Institute of Science, Israel)
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Working with Hybrigenics staff is more like having a collaborator than a service provider…staff is very knowledgeable and highly responsive..their expertise and novel methodology gives high hit rel...

Dr. Bhuminder Singh (Vanderbilt University, USA)
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Hybrigenics yeast two-hybrid screening is unparalleled in terms of completeness and quality of service. Moreover, their services are a tremendous value, as we could not set it up in our lab for ev...

Dr. Scott Hiebert (Vanderbilt University, USA)
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My laboratory carried out a Y2H screen using a brain fetal library to find proteins interacting with a cleaved domain of a transmembrane protein. Every part of the procedure was clearly explained ...

Dr. Bernard Rogister (University of Liège, Belgium)
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I have been very happy with the results. They have given us numerous leads for our research. I would definitely use Hybrigenics services again.

Dr. James Schoelz (University of Missouri, USA)
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My laboratory carried out a Y2H screen with Hybrigenics using a human fibroblast cDNA library. I was very pleased with the results that we got. When I first contacted Hybrigenics about carrying ou...

Dr. Grant Stewart (University of Birmingham, United Kingdom)
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I requested Hybrigenics to perform a Y2H screen to test specific protein-protein interactions in the model plant Arabidopsis thaliana, the system I am working on. The results obtained by Hybrigenic...

Dr. Jose M. Estevez (University of Buenos Aires, Argentina)
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As a fundamentalist researcher in pain neurophysiology, seeking interaction partners of our potent targets is undoubtedly necessary to unravel underlying mechanisms and address our hypothesis. Afte...

Dr. Nicolas Beaudet (Sherbrooke University, Canada)
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Hybrigenics was up to par for their services, starting from the time the contract was established. There was absolutely no down time on their end. Our request was executed as we wished.

Dr. Pascale Nantermet (Merck & Co, USA)
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Hybrigenic’s two-hybrid service is really quite impressive, and their people are a pleasure to work with, I highly recommend them. And, it doesn’t matter how little you pay your post docs, you can’...

Dr. Mike Schopperle (Harvard Medical School, USA)
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If you are a small, cost-sensitive lab and you are considering a yeast two-hybrid approach, Hybrigenics offers a compelling package of experienced scientists, vectors, procedures, cDNA libraries, r...

Dr. Howard Gershenfeld (University of Texas Southwestern, USA)
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We have used Hybrigenics services to screen a cDNA library of Arabidopsis for six different baits. We have obtained very good results for all of them. We have found the support service remarkably ...

Pr. Federica Brandizzi (Michigan State University, USA)
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The technical and sales staff at Hybrigenics have been very supportive in our project so far. They have worked with us every step of the way, on a project that has had numerous technical challenges...

Dr. Alex Bassuk (University of Iowa, USA)
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I have had two Y2H screens conducted by Hybrigenics. I found my contacts to be helpful and friendly, and they gave clear advice on the pros and cons of particular types of libraries and of differen...

Dr. Phil Woodman (Manchester University, United Kingdom)
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I used Hybrigenics Y2H services to identify new protein-protein interactions using our protein of interest as a bait against their human placenta library. The results of the screening were very sat...

Dr. Susana Llanos (National Cancer Research Centre, Spain)
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Welcome to Hybrigenics Services,

Your number 1 partner for protein interaction studies.

Upgrade to ULTImate Y2HTM and associated services.

Scientific assistance – Tailored approach – Exhaustive screening of highly complex libraries – Fully analyzed results.

Accelerate your research.

Fast and efficient service – Publication grade pictures – Detailed methods and experiment reports.

Your science, your satisfaction.

Scientific assistance from project design to full review of the results with you.

Hybrigenics Services announce the launch of its new service:

ULTImate YChemH

an in-yeast compound profiling service that aims to identify the protein targets of a small molecule

This new service, based on the yeast 3-hybrid technology, allows for in-vivo detection of protein-ligand interactions.
It tackles crucial issues in drug discovery and development such as target identification, off-target side effects and toxicity and drug repositionning.

Contact our team of experts for a project discussion now