Our work with Hybrigenics aimed to deconvolute the potential target of a promising screening hit that we had previously identified in a phenotypic HTS campaign. Hybrigenics not only carried out the YChemH service itself but also organized the synthesis of chemical probes required for the conduct of the YChemH screen.
We were thrilled to see how goal-oriented they realized the project proposal which resulted in an unambiguous result that meanwhile has been confirmed in several follow-up assays in our hands.
That was beyond our expectations in terms of the speed and the robustness with which we accomplished our goal. What we appreciated most about working with Hybrigenics was their effort to develop a deep understanding of our needs and their ability to deliver sustainable results.
Matthias Baumann (Lead Discovery Center, Dortmund, Germany) -