We successfully carried out a Y2H screen with Hybrigenics. We obtained excellent advice on designing our bait and choosing the best library for our studies. A large number of candidate interacting proteins were rapidly uncovered and the results were easy to analyze with the excellent bioinformatics report prepared by our personalized contact at Hyrigenics.
This screen led to at least three publications including a recent one in PNAS. Given their excellent service and their professionalism, I will not hesitate to use Hybrigenics again to continue discovering new protein-protein interactions.
Jean-Francois Cote (IRCM, Montréal, Canada) -