- Interaction Discovery
- Target Deconvolution
- Our libraries
- Our references
- Resource center
Neuchatel, Lausanne, Geneva, Switzerland - July 21-25
Petra Tafelmeyer, director of scientific project, will be travelling from Neuchâtel to Geneva, from July 21st to July 25th.
She will be happy to meet you if you are in the area and discuss your project.
Feel free to contact us here to arrange a meeting with her.
Paris, France - July 22
Happy birthday Yeast Two-Hybrid!
Today, It's been 25 years since The Yeast Two-Hybrid (Y2H) system was first described by Drs Stanley Fields and Ok-Kyu Song then at the Department of Microbiology of the State University of New York at Stony Brook in their seminal article entitled “A novel genetic system to detect protein–protein interactions” published in Nature on July 20th,1989.
Yeast two-hybrid benefits from unique technical advantages: in vivo, direct and sensitive method. It quickly became a major technique of the post-genomic era that allowed the large scale characterization of novel gene functions.
Dozens of thousands of publications to date are based on yeast two-hybrid results.
At Hybrigenics, we are proud to say we have made key improvements to overcome the limitations of the initial versions:
* False positives are no longer an issue as they are flagged thanks to a scoring system comparing results with our database of over 8,000 screens.
* False negatives are limited thanks to Hybrigenics mating protocol to screen exhaustively highly complex domain libraries, ensuring that different regions of all expressed proteins are tested for their interaction with the bait.
* Specific post-translational modifications absent in yeast can be introduced by modifying the yeast strain. See our ULTImate Y2H+1 offer.
* Nuclear targetting is not a prerequisite as specific protocols can be used for membrane proteins. Learn more on MBmate Y2H.
Contact us to learn more on the latest improvements of the Y2H technology and how it could benefit your research!
Heidelberg, Germany - July 18-19
Hybrigenics Services is glad to sponsor the EMBL 40th Anniversary Reunion.
The meeting will take place in Heidelberg in Germany, from Friday 18th to Saturday 19th July, 2014 and will bring together more than 900 participants worldwide to celebrate EMBL work and contribution to life sciences. You can find the program here.
Stéphanie Blachon, scientific project leader, and Samy Sakr, sales engineer, will attend this event and will be happy to meet you and discuss your project.
Feel free to contact us here to arrange a meeting with our team.
Portland, OR, USA - July 12-16
Meet us at the annual scientific meeting of the American Society of Plant Biologists (ASPB), Plant Biology 2014.
This event will take place from July 12th to 16th in Portland, Oregon.
Petra Tafelmeyer, director of scientific project and Brent Passer, director of business development US, will attend the meeting. They will be waiting for your visit, booth #321.
Feel free to contact us to arrange a meeting with our team.
Paris, France - July 10
Hybrigenics Services is now on Twitter!
We like to interact so follow us via @
Lille, France - July 7-8
Bruno Mainnemard, sales engineer, will be visiting the Pasteur Institute and Biology Institute in Lille from July 7th to 8th.
Feel free to contact him here to arrange a meeting and discuss your project.
Rouen, France - July 2-4
Hybrigenics Services is glad to sponsor the French Medicinal Chemical Society for their 50th edition of the International Conference on Medicinal Chemistry (RICT).
The symposium will take place from July 2nd to 4th, 2014 in Rouen, France and will gather more than 600 scientists around the world to focus on "Interfacing Chemical Biology and Drug Discovery".
Feel free to go to their website for more information or to read Professor Dario Nerio (ETH Zürich) editorial of the conference.