The Protein Interactions Expert


Two Soybean ULTImate Libraries available for screening

Paris, France - April 22

We just released two new Soybean (Glycine max) cDNA libraries:

- One was prepared from water stressed leaves and roots

- The other one is from leaves, shoots and roots infected with B. japonicum.

Feel free to contact us for more information about these libraries or to launch a screen.

Cell Biology: new articles in J.Cell Sci. and Plos One

Paris, France - April 18

Two new articles by Hybrigenics' customers have just been published.

Yun-Jin Jiang and colleagues wanted to further understand the function of Mind bomb (Mib) and Mib2 in the Notch signaling pathway. Several yeast two-hybrid screens were performed on two distinct Zebrafish libraries and allowed to identify new classes of mind bomb-interacting proteins. Along with other experiments and previous studies, these results brought to light a regulating network involving several Mib proteins.

This work was published in PLOS ONE on April 8, 2014 and can be read online here.

Also, Christos Samakovlis and his team who study wound healing in Drosophila used our yeast two-hybrid screening service to identify pathways mediating injury responses. The screening revealed an RTK-dependent activation mode for Src kinases and their central functions during epidermal wound healing in vivo.

This work was published in the Journal of Cell Science on April 15, 2014.

Marcela Nuñez, sales engineer, will be in the UK

London and Oxford, UK - April 15-17

Marcela Nuñez, sales engineer, will be traveling in the UK.

She will be in London on Tuesday April15th and then in Oxford from Wednesday April 16th to Thursday April17th.

If you want to arrange a meeting with her, feel free to contact us here and she will be happy to meet you and discuss your project.

Hybrigenics customers detail in Nature Cell Biology the role of the R-SNARE Sec22b in plasma membrane expansion

Paris, France - April 11

A new article by Hybrigenics'customers has just been published.

Thierry Galli's and Cathy Jackson's teams study neuronal cell growth and the mechanisms behind plasma membrane (PM) expansion.

They report here that the R-SNARE Sec22b localizes to the endoplasmic reticulum (ER) and is necessary for both axonal and dendritic growth. Using Hybrigenics ULTImate Y2H screening service, they found an interaction between Sec22b and Syntaxin1, a plasma membrane Q-SNARE. They further demonstrate that the close apposition of the ER and the plasma membrane mediated by Sec22 and Syntaxin1 generates a non-fusogenic SNARE bridge contributing to plasma membrane expansion.

This article was published in Nature Cell Biology on April 6, 2014.

Meet us at the AACR meeting

San Diego, CA, USA - April 05-09

Meet us at the 105th Annual Meeting of the American Association for Cancer Research.

The event will be held April 5-9, 2014, in San Diego, California. Hybrigenics Services is glad to participate to this meeting.

Brent Passer, Director of Business Development for USA, will attend the event. Feel free to contact us to arrange a meeting with him.

We are looking forward to seeing you there!

Hybrigenics Services introduces you to Helixio, its sister activity

Paris, France - April 03

Helixio provides full customised Microarray & Next Generation Sequencing services applied to any human, animal, plant or microbial samples and address key biological issues by enabling Gene Expression Profiling, Exome Resequencing after Target Enrichment, SNP Detection, CNV identification and much more.

Browse Helixio website to learn more on Hybrigenics genomics branch.

Read Hybrigenics press release here.

Helixio logo

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