The Protein Interactions Expert

Interaction Discovery Services

two pieces of a puzzle assembled together

Discover a world of protein interactions

Discover novel protein partners for your favorite protein, DNA, short RNA or small bioactive molecule thanks to Hybrigenics proprietary ULTImate process.

ULTImate Y2H™ is the most comprehensive yeast two-hybrid technology available to date to identifiy protein protein interactions.

It combines highly complex domain libraries, exhaustive screening, in-depth bioinformatics analysis and exclusive technical advice and project follow-up. Thanks to specific protocols, we can screen any protein including transcription factors, membrane-bound proteins and proteins requiring a co-factor or a post-translational modification.


We developed variations of our core technology offering the same key benefits:

ULTImate Y1H for DNA-protein interaction discovery

ULTImate RNA Y3H for RNA-protein interaction discovery

 ULTImate YChemH for small molecule-protein interaction discovery (target deconvolution)


More than 2,500 customers worldwide have trusted us for their protein interaction project.

Be the next one and accelerate your research!


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